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黃偉倫

黃偉倫 兼任助理教授  Wei-Lun Huang

 

  辦公室電話：(06)2353535 #6733

  辦公室地點：奈米醫學研究中心 (成大醫院門診大樓)

  電子信箱：allenhuang@mail.ncku.edu.tw   r4215652@gmail.com

  學術成大：黃 偉倫

 

開授課程

大學部

  上學期︰普通生物學、醫技導論、專題研究實驗

  下學期︰專題研究實驗

碩士班

  上學期︰無

  下學期︰無

MyLab實驗室研究方向

本實驗室主要研究方向在將各種新興跨領域技術 (奈米技術、電子顯微鏡、AI技術與微流道晶片等)導入生物醫學應用進行轉譯研發，例如利用原先作為太陽能產氫的石墨烯量子點奈米材料應用於光動力癌症治療及生醫診斷訊號的放大；利用特殊樣本載台設計使用電子顯微鏡觀察液態生物樣本(如胞外體)；利用AI技術加速細菌藥敏性檢測；利用微流道晶片分析癌細胞的藥物敏感性。

指導學生

成大醫技所碩士班

邱○文 (112級)

成大醫技系

王○琇 (112級)、陳○萱 (112級)、余○宏 (112級)、方○廷 (113級)、曾○廉 (114級)、黃○緯 (114級)

成大其他碩士班

林○泰 (材料所112級)、陳○翰 (材料所113級)

其他大學部

Gabriel Lin (University College London)

指導學生之特殊榮譽

  1. 2020國際奈米科技奧林匹亞(INO)國家代表隊選拔賽全國亞軍 (王○琇、陳○萱)
  2. 國立成功大學110年「大學生專題研究成果海報競賽」佳作獎 (陳○萱)
  3. 國立成功大學醫學院110年「暑期研究計畫」醫學科研組優選獎 (方○廷)
  4. 國立成功大學111年「大學生專題研究成果海報競賽」佳作獎 (方○廷)
  5. 「2022全國三分鐘生科論文口說競賽」銅獎 (方○廷)
  6. 國立成功大學醫學院111年「暑期研究計畫」醫學科研組優選獎 (曾○廉)

期刊論文

  1. Chun-Yan Shih, Pei-Ting Wang, Wei-Pang Chung, Wen-Hsiu Wang, I-Ting Chiang, Wu-Chou Su, Wei-Lun Huang* and Hsisheng Teng*. Concise nanotherapeutic modality for cancer involving graphene oxide dots in conjunction with ascorbic acid. Nanoscale 2023 in press. (SCIE; IF=8.307)
  2. Yung-Chien Chang, Min-Chieh Shieh, Yen-Hsuan Chang, Wei-Lun Huang, Wu-Chou Su, Fong-Yu Cheng, Chun Hei Antonio Cheung. Development of a cancer cells self-activating and miR-125a-5p ex-pressing poly-pharmacological nanodrug for cancer treatment. International Journal of Molecular Sciences 2022 Aug, 50(2): 102. (SCIE; IF=6.208)
  3. Wei-Pang Chung, Wei-Lun Huang, Chun-Hui Lee, Hui-Ping Hsu, Wan-Ling Huang, You-Yu Liu, Wu-Chou Su. PI3K inhibitors in trastuzumab-resistant HER2-positive breast cancer cells with PI3K pathway al-terations. American Journal of Cancer Research 2022 Jul, 12(7): 3067-3082. (SCIE; IF=5.942)
  4. Jordan Cheng, Marco Morselli, Wei-Lun Huang, You Jeong Heo, Thalyta Pinheiro-Ferreira, Feng Li, Fang Wei, David Chia, Hua Jun, Kenneth Cole, Wu-Chou Su, Matteo Pellegrini, David TW Wong. Plasma Contains Ultra-short Single-stranded DNA in Addition to Nucleosomal Cell-Free DNA. iScience 2022 Jul, 25(7): 154554. (SCIE; IF=6.107)
  5. Wei-Pang Chung, Wei-Lun Huang, Wei-An Liao, Chun-Hua Hung, Chi-Wu Chiang, Chun Hei Antonio Cheung, Wu-Chou Su. FTY720 in resistant human epidermal growth factor receptor 2-positive breast cancer. Scientific Reports 2022 Jan; 12(1): 241. (SCIE; IF=4.996)
  6. Chun-Yan Shih, Wei-Lun Huang, I-Ting Chiang, Wu-Chou Su, Hsisheng Teng. Biocompatible hole scav-enger-assisted graphene oxide dots for photodynamic cancer therapy. Nanoscale 2021 May; 13(8): 8431-8441. (Front Cover) (SCIE; IF=8.307)
  7. Wei-Pang Chung, Wei-Lun Huang, Wei-An Liao, Wan-Ling Huang, You-Yu Liu, Wu-Chou Su. Develop-ment of the CK-MB-1 trastuzumab-resistant HER2-positive breast cancer cell line and xenograft ani-mal models. Cancer Medicine 2021 Mar; 10(7): 2370-2379. (SCIE; IF=4.711)
  8. Chun-Yan Shih, Pei-Ting Wang, Wu-Chou Su, Hsisheng Teng, Wei-Lun Huang*. Nanomedicine-based strategies assisting photodynamic therapy for hypoxic tumors: state-of-the-art approaches and emerging trends. Biomedicines 2021 Feb, 9(2): 137. (SCIE; IF=4.757)
  9. Chen-Hsueh Lin, Yu-Sheng Chen, Wei-Lun Huang, Tzung-Chin Hung, Ten-Chin Wen. Hydroxyapatite formation with the interface of Chitin and Chitosan. Journal of the Taiwan Institute of Chemical En-gineers 2021 Jan, 118: 294-300. (SCIE; IF=5.477)
  10. Michael Tu, Jordan Cheng, Yi-Lin Chen, Wen-Chien Jea, Wan-Li Chen, Chien-Jung Chen, Chung-Liang Ho, Wei-Lun Huang, Chien-Chung Lin, Wu-Chou Su, Qianlin Ye, Josh Deignan, Wayne Grody, Feng Li, David Chia, Fang Wei, Wei Liao, David T.W. Wong, Charles M Strom. Electric Field Induced Release and Measurement (EFIRM): Characterization and technical validation of a novel liquid biopsy platform in plasma and saliva. Journal of Molecular Diagnostics 2020 Aug; 22(8): 1050-1062. (SCIE; IF=5.341)
  11. Feng Li, Fang Wei, Wei-Lun Huang, Chien-Chung Lin, Liang Li, Macy M. Shen, Qingxiang Yan, Wei Liao, David Chia, Michael Tu, Jason H. Tang, Ziding Feng, Yong Kim, Wu-Chou Su, David T.W. Wong. Ultra-short circulating tumor DNA (usctDNA) in plasma and saliva of non-small cell lung cancer (NSCLC) pa-tients. Cancers 2020 Jul; 12(8): 2041. (SCIE; IF=6.575)
  12. Kundan Sivashnamugan#, Wei-Lun Huang# (# Equal Contribution First Author), Chen-Hsueh Lin, Jiunn-Der Liao, Chien-Chung Lin, Wu-Chou Su, Ten-Chin Wen. Bimetallic nanoplasmonic gap-mode SERS substrate for distinguishing lung normal and cancer-derived exosomes. Journal of the Taiwan Insti-tute of Chemical Engineers 2017 Nov; 80: 149-155. (SCIE; IF=5.477)
  13. Te-Fu Yeh, Wei-Lun Huang, Chung-Jen Chung, Hsin-Yu Chang, Chun-Yu Lin, Wu-Chou Su, Ching Cheng, Shean-Jen Chen, Hsisheng Teng. Elucidating quantum confinements in graphene oxide quan-tum dots for high-quality photoluminescence emissions. Journal of Physical Chemistry Letters 2016 Jun; 7(11): 2087-2092. (SCIE; IF=6.888)
  14. Chien-Chung Lin, Wei-Lung Huang, Fang Wei, David T. Wong, Wu-Chou Su. Emerging platform using liquid biopsy to detect EGFR mutations in lung cancer. Expert Review of Molecular Diagnostics 2015 Nov; 15(11): 1427-1440. (SCIE; IF=5.67)
  15. Wei-Lung Huang, Fang Wei, David T. Wong, Chien-Chung Lin, Wu-Chou Su. The emergent landscape of detecting EGFR mutations using circulating tumor DNA in lung cancer. BioMed Research Interna-tional 2015 Sep; 2015: 340732. (SCIE; IF=3.246)
  16. I-Fang Cheng, Wei-Lun Huang, Tzu-Ying Chen, Chien-Wei Liu, Yu-De Lin, Wu-Chou Su. Antibody-free isolation of rare cancer cells from blood based on 3D lateral dielectrophoresis. Lab on a Chip 2015 Jun; 15(14): 2950-2959. (Back Cover) (SCIE; IF=7.517)
  17. Chien-Chung Lin, Hsuan-Heng Yeh, Wei-Lun Huang, Wu-Chou Su. Metformin enhances cisplatin cyto-toxicity by suppressing Stat3 activity independently of the LKB1-AMPK-MTOR pathway. American Journal of Respiratory Cell and Molecular Biology 2013 Aug; 49(2): 241-250. (SCIE; IF=7.748)
  18. Hao-Chen Wang, Hsuan-Heng Yeh, Wei-Lun Huang, Chien-Chung Lin, Wen-Pin Su, Helen H. W. Chen, Wu-Wei Lai, Wu-Chou Su. Activation of the signal transducer and activator of transcription 3 pathway up-regulates estrogen receptor-β expression in lung adenocarcinoma cells. Molecular Endocrinology 2011 Jul; 25(7): 1145-1158. (SCIE; IF=5.051)
  19. Wei-Lun Huang, Hsuan-Heng Yeh, Chien-Chung Lin, Wu-Wei Lai, Jang-Yang Chang, Wen-Tsan Chang, Wu-Chou Su. Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical iso-lated human cancer cells. Molecular Cancer 2010 Dec; 9: 309. (SCIE; IF=41.444)
  20. Chien-Chung Lin#, Wei-Lun Huang# (# Equal Contribution First Author), Wen-Pin Su, Helen H. W. Chen, Wu-Wei Lai, Jing-Jou Yan, Wu-Chou Su. Single cell phospho-specific flow cytometry can detect dynam-ic changes of phospho-Stat1 level in lung cancer cells. Cytometry Part A 2010 Nov; 77A(11): 1008-1019. (SCIE; IF=4.714)
  21. Wei-Shio Hor, Wei-Lun Huang, Yee-Shin Lin, Bei-Chang Yang. Cross-talk between tumor cells and neu-trophils through the Fas (APO-1, CD95)/FasL system: human glioma cells enhance cell viability and stimulate cytokine production in neutrophils. Journal of Leukocyte Biology 2003 Mar; 73 (3): 363-368. (SCIE; IF=6.011)

主辦、參與國際會議

主辦國際會議

2023 Japan-Taiwan Workshop@Tsukuba, International Center for Materials Nanoarchitectonics (MANA), Tsukuba, Japan.

2023 Japan-Taiwan Nanotechnology Workshop, Geochemical Research Center (GRC), The University of Tokyo, Tokyo, Japan.

2023 臺灣奈米生醫學會年會暨國際研討會 (International Conference on Precision Nanomedicine in Theranostics & The 2023 Annual Meeting of Taiwan Nanomedicine Society), Evergreen Laurel Hotel, Taichung, Taiwan.

2022 臺灣奈米生醫學會年會暨國際研討會 (International Conference on Precision Nanomedicine in Theranostics & The 2022 Annual Meeting of Taiwan Nanomedicine Society), Sheraton Hsinchu Hotel, Hsinchu, Taiwan.

2021 臺灣奈米生醫學會年會暨國際研討會 (International Conference on Precision Nanomedicine in Theranostics & The 2021 Annual Meeting of Taiwan Nanomedicine Society), Shangri-La Far Eastern Plaza Hotel, Tainan, Taiwan.

2020 臺灣奈米生醫學會年會暨研討會 (The 2022 Annual Meeting of Taiwan Nanomedicine Society), Academia Sinica, Taipei, Taiwan.

2018 WIN-NCKU Workshop, Waterloo Institute for Nanotechnology, Canada.

2018 台日韓奈米生醫研討會 (2018 Taiwan-Japan-Korea Trilateral Conference on Nanomedicine), Shangri-La Far Eastern Plaza Hotel, Tainan, Taiwan.

參與國際會議

1. Wei-Lun Huang, Wu-Chou Su. Potential roles of cancer derived extracellular vesicles in lung cancer metastasis and progression. 2019 International Society for Extracellular Vesicles (ISEV) Annual Scientific Meeting, Kyoto, Japan.

2. Wei-Lun Huang, Kundan Sivashnamugan, Ten-Chin Wen, Wu-Chou Su. Identifying potential biomarkers for lung cancer from the cancer derived exosomes using the nano gap-mode surface-enhanced Raman scattering (SERS). 2018 International Society for Extracellular Vesicles (ISEV) Annual Scientific Meeting, Barcelona, Spain.

3. Wei-Lun Huang*, Kundan Sivashnamugan* (*Equal Contribution First Author), Ten-Chin Wen, Wu-Chou Su. Distinguishing lung normal and cancer-derived exosomes, the naturally occurring liposome-like vesicles, using SERS. Lipidomics and Bioactive Lipids in Metabolism and Disease, Tahoe City, USA.

4. Wei-Lun Huang, Wu-Chou Su. Detection of actionable EGFR mutations in secretory extracellular vesicles (EV) from non-small cell lung cancer patients. 21th World Congress on Advances in Oncology & 19th International Symposium on Molecular Medicine, Athens, Greece. (Invited Speech)

5. Wei-Lun Huang, Chien-Chung Lin, Shang-Rung Wu, Wu-Chou Su. The role of lung cancer derived extracellular vesicles in tumor progression. 2016 International Society for Extracellular Vesicles (ISEV) Annual Scientific Meeting, Rotterdam, the Netherlands.

6. Wei-Lun Huang, Chien-Chung Lin, Shang-Rung Wu, Wu-Chou Su. Lung cancer derived extracellular vesicles triggered oncogenic signals and increased vascular permeability in an autocrine/paracrine fashion. 2015 International Society for Extracellular Vesicles (ISEV) Annual Scientific Meeting, Washington DC, USA.

8. Wei-Lun Huang, Chien-Chung Lin, Wu-Chou Su. Evaluation of the roles of nanometer sized extracellular vesicles on lung cancer progression: biological functions and clinical applications. 2013 ISEV Workshop: EV isolation and Characterization, Budapest, Hungary. (Invited Speech, only 66 selected participants)

9. Wei-Lun Huang, Chien-Chung Lin, Wu-Chou Su. Evaluation of the roles of nanometer sized extracellular vesicles on lung cancer progression. 2013 International Society for Extracellular Vesicles (ISEV) Annual Scientific Meeting, Boston, USA.

10. Wei-Lun Huang, Chien-Chung Lin, Wu-Chou Su. Isolation of tumor associated exosomes from clinical samples using the ultra-filtration method. 2012 International Society for Extracellular Vesicles (ISEV) Annual Scientific Meeting, Gothenburg, Sweden.

11. Wei-Lun Huang, Hsuan-Heng Yeh, Wu-Chou Su. Stat3 positively regulates IL-6 expression in lung cancer cells. 2008 American Association for Cancer Research (AACR) Annual Meeting, San Diego, USA.

教學、研究國際交流

  • 至國外學術機構訪問次數： UCLA訪問學者：2020/01-2020/02
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