蔡慧頻
蔡慧頻 臨床副教授 Huey-Pin Tsai
實驗室電話:06-2353535轉2653 or 2616
辦公室地點:成大醫院病理部臨床病毒實驗室
電子信箱: tsaihp@mail.ncku.edu.tw
學術成大:蔡慧頻
開授課程
大學部
上學期︰臨床病毒學實習、普通生物學
下學期︰臨床病毒學、臨床病毒學實驗、檢驗室品管
MyLab實驗室研究方向
- 1. 病毒檢驗新方法評估確效
- 2. 開發新的臨床病毒技術,與臨床醫師共同合作評估成效,以期建立更準確的方法提供臨床診斷服務。
- 3. 病毒抗藥性研究
- 臨床病毒學、開發病毒檢驗新方法、病毒抗藥性研究
歷年實驗室研究成員
碩士班:
107學年 郭O佑
112 學年 黃O庭
大學部暑期研究生:
110 學年 陳O文
榮譽及獎勵
1.教學:
- 榮獲成大醫院病理部107、108和112年度教學成效評良績優排行組長獎。(108(獎)成附醫病張字第0014號, 109(獎)成附醫病張字第0007號, 113(獎)成附醫病蔡字第0011號)
- 榮獲成大醫院112年教學改善PDCA標竿獎勵活動-教師教學評估改善-佳作。(112(教)成附醫揚字第V239號)
- 榮獲成大醫院「111年度教學特優教師遴選-教學熱心臨床教師」。(112(教)成附醫揚字第V057號)
- 榮獲成大醫院「109年教學創新與教學成果發表競賽」教學創新第一名 (第一作者)。(109(教)成附醫揚字第V104號)
- 榮獲成大醫院「107年度教學特優教師遴選-教學熱心臨床教師」。(108(教)成附醫揚字第V069號)
- 榮獲107年度成大醫院「教學創新與教學成果發表競賽」標竿學習優等(第一作者)。(107(教)成附醫揚字第V103號)
- 參加「100年教學創新與教學成果發表競賽」活動榮獲「教學成果組」佳作。(共同作者)(100(教)成附醫楊字第V056號)
- 榮獲病理部第一屆醫檢師菁英訓練計劃導師獎。(100(獎)成附醫病顏字第0018號)
2.研究:
- 榮獲成大醫院病理部100, 105, 107, 109, 112 年度論文RPI積分醫檢師組第一名。(101(獎) 成附醫病顏字第0002號, 106(獎)成附醫病張字第0005號, 108(獎)成附醫病張字第0006號, 110(獎)成附醫病蕭字第0006號113(獎), 成附醫病蔡字第0006號)
- 榮獲成大醫院病理部110, 111年度論文RPI積分醫檢師組第二名。(111(獎) 成附醫病蕭字第0004號, 112(獎)成附醫病蔡字第0007號)
- 榮獲110年度台灣醫檢學會年會學術論文獎(臨床應用組)。
- 榮獲105和107年度台灣醫檢學會年會優秀壁報論文獎。(第一作者)
- 榮獲100和108年亞太醫檢學會血清病毒組壁報論文獎(Distinguished Paper Award)。(101(賀) 成附醫病顏字第0001號, 108年為通訊作者)
- 榮獲106年度台灣醫檢學會年會學術論文獎(臨床應用組)。
- 榮獲106年度成杏基金會優秀論文獎(臨床醫學組)。
- 榮獲104和105年度成大醫院醫療科技研究計劃實驗操作組第一名。
3.臨床服務:
- 榮獲成大醫院112年度模範公務人員。
- 113年1月取得台灣醫檢學會MT4進階醫檢師證書。
4.其他:
- 榮獲106年度成功大學醫學檢驗生物技術學系傑出系友。
期刊論文
- Wang JR, Tsai HP, Chen PF, Lai YJ, Yan JJ, Kiang D, Lin KH, Liu CC, Su IJ. 2000 Aug. An outbreak of enterovirus 71 infection in Taiwan, 1998. II. Laboratory diagnosis and genetic analysis. J Clin Virol. 17(2):91-9. Scopus number of citations: 55, 5 year IF: 5.6
- Tsai HP, Kuo PH, Liu CC, Wang JR. 2001 Jan. Respiratory viral infections among pediatric inpatients and outpatients in Taiwan from 1997 to 1999. J Clin Microbiol. 39(1):111-8. Scopus number of citations:137 , 5 year IF: 6.9
- Shan YS, Lee PC, Wang JR, Tsai HP, Sung CM, Jin YT. 2001 Dec. Fibrosing cholestatic hepatitis possibly related to persistent parvovirus B19 infection in a renal transplant recipient. Nephrol Dial Transplant. 16(12):2420-2. Scopus number of citations:28, 5 year IF:5.8
- Wang JR, Tuan YC, Tsai HP, Yan JJ, Liu CC, Su IJ. 2002 Jan. Change of major genotype of enterovirus 71 in outbreaks of hand-foot-and-mouth disease in Taiwan between 1998 and 2000. J Clin Microbiol. 40(1):10-5. Scopus number of citations:151 , 5 year IF: 6.9
- Wang JR, Tsai HP, Huang SW, Kuo PH, Kiang D, Liu CC. 2002 Dec. Laboratory diagnosis and genetic analysis of an echovirus 30-associated outbreak of aseptic meningitis in Taiwan in 2001. J Clin Microbiol. 40(12):4439-44. Scopus number of citations:50, 5 year IF: 6.9
- Tsai HP, Wang HC, Kiang D, Huang SW, Kuo PH, Liu CC, Su IJ, Wang JR. 2006 Aug. Increasing appearance of reassortant influenza B virus in Taiwan from 2002 to 2005. J. Clin Microbiol. 44(8):2705-13. Scopus number of citations:24, 5 year IF: 6.9
- Huang SC, Hsu YW, Wang HC, Huang SW, Kiang D, Tsai HP, Wang SM, Liu CC, Lin KH, Su IJ, Wang JR. 2008 Feb. Appearance of intratypic recombination of enterovirus 71 in Taiwan from 2002 to 2005. Virus Res. 131(2):250-9. Scopus number of citations:67, 5 year IF: 4.0
- Wang HC, Huang SW, Wang SW, Tsai HP, Kiang D, Wang SM, Liu CC, Su IJ, Wang JR. 2008 Nov. Co-circulating genetically divergent A2 human metapeumovirus strains among children in southern Taiwan. Arch Virol. 153:2207-2213. Scopus number of citations:12, 5 year IF: 2.4
- Huang SW, Hsu YW, Smith DJ, Kiang D, Tsai HP, Lin KH, Wang SM, Liu CC, Su IJ, Wang JR. 2009 Nov. Reemergence of enterovirus 71 in 2008 in taiwan: dynamics of genetic and antigenic evolution from 1998 to 2008. J.Clin. Microbiol. 47(11):3653-62. Scopus number of citations:173, 5 year IF:6.9
- Yeh YM, Chang KC, Chen YP, Kao LY, Tsai HP, Ho CL, Wang JR, Jones D, Chen TY. 2010 Dec. Large B cell lymphoma presenting initially in bone marrow, liver and spleen: an aggressive entity associated frequently with haemophagocytic syndrome. Histopathology 57(6):785-795. Scopus number of citations::30, 5 year IF:5.1
- Tsai HP, Wang JR. 2011. Influenza viruses and 2009 H1N1 pandemic influenza virus. Formosan J Med 15(3): 252-260. Scopus number of citations:0, 5 year IF:3.3
- Tsai HP, Huang SW, Wu FL, Kuo PH, Wang SM, Liu CC, Su JJ, Wang JR. 2011 Sep. An echovirus 18-associated outbreak of aseptic meningitis in Taiwan: epidemiology and diagnostic and genetic aspects. J. Med. Microbiol. 60(pt9):1360-5. Scopus number of citations:27, 5 year IF:2.7
- Wang SL, Chi CY, Kuo PH, Tsai HP, Wang SM, Liu CC, Su IJ, Wang JR. 2013 Sep. High-incidence of human adenoviral co-infections in Taiwan. PLoS One. 20;8(9):e75208. Scopus number of citations:25, 5 year IF:3.8
- Huang SW, Cheng HL, Hsieh HY, Chang CL, Tsai HP, Kuo PH, Wang SM, Liu CC, Su IJ, Wang JR. 2014 Apr. Mutations in the non-structural protein region contribute to intra-genotypic evolution of enterovirus 71. J Biomed Sci. 26;21(1):33. Scopus number of citations:27, 5 year IF:10.9
- Wang YF, Shen FC, Wang SL, Kuo PH, Tsai HP, Liu CC, Wang JR, Chi CY. 2016 May. Molecular Epidemiology and Clinical Manifestations of Adenovirus Respiratory Infections in Taiwanese Children. Medicine (Baltimore). 95(18):e3577. Scopus number of citations:25, 5 year IF:1.9
- Tsai HP, Tsai YY, Lin IT, Kuo PH, Chen TY, Chang KC, Wang JR. 2016 Aug. Comparison of Two Commercial Automated Nucleic Acid Extraction and Integrated Quantitation Real-Time PCR Platforms for the Detection of Cytomegalovirus in Plasma. PLoS One. 5;11(8):e0160493. Scopus number of citations:14, 5 year IF:3.8
- Tsai HP, Tsai YY, Lin IT, Kuo PH, Chang KC, Chen JC, Ko WC, Wang JR. 2016 Oct. Validation and Application of a Commercial Quantitative Real-Time Reverse Transcriptase-PCR Assay in Investigation of a Large Dengue Virus Outbreak in Southern Taiwan. PLoS Negl Trop Dis. 12;10(10):e0005036. Scopus number of citations:11, 5 year IF:4.1
- Huang SW, Huang YH, Tsai HP, Kuo PH, Wang SM, Liu CC, Wang JR. 2017 Nov. A selective bottleneck shapes the evolutionary mutant spectra of enterovirus A71 during viral dissemination in humans. J Virol. 91(23):e01062-17. Scopus number of citations:31, 5 year IF:4.9
- Yen CJ, Ai YL, Tsai HW, Chan SH, Yen CS, Cheng KH, Lee YP, Kao CW, Wang YC, Chen YL, Lin CH, Liu T, Tsai HP, Wang JR, Su IJ, Huang W. 2018 Sep; Hepatitis B virus surface gene pre-S2 mutant as a high-risk serum marker for hepatoma recurrence after curative hepatic resection. Hepatology. 68(3):815-826. Scopus number of citations:28, 5 year IF:15.6
- Chen HR, Chao CH, Liu CC, Ho TS, Tsai HP, Perng GC, Lin YS, Wang JR, Yeh TM. 2018 Apr. Macrophage migration inhibitory factor is critical for dengue NS1-induced endothelial glycocalyx degradation and hyperpermeability. PLoS Pathog. 2018 Apr 27;14(4):e1007033. Scopus number of citations:54, 5 year IF:6.7
- Wang YF, Chang CF, Tsai HP, Chi CY, Su IJ, Wang JR. 2018 May. Glycan-binding preferences and genetic evolution of human seasonal influenza A(H3N2) viruses during 1999-2007 in Taiwan. PLoS One. 10;13(5):e0196727. Scopus number of citations:9, 5 year IF:3.8
- Hung SJ, Hsu YM, Huang SW, Tsai HP, Lee LYY, Hurt AC, Barr IG, Shih SR, Wang JR. 2020 Jan. Genetic variations on 31 and 450 residues of influenza A nucleoprotein affect viral replication and translation. J Biomed Sci. 6;27(1):17. Scopus number of citations:3, 5 year IF:10.9
- Lee NY, Li CW, Tsai HP, Chen PL, Syue LS, Li MC, Tsai CS, Lo CL, Hsueh PR, Ko WC. 2020 Jun; A case of COVID-19 and pneumonia returning from Macau in Taiwan: Clinical course and anti-SARS-CoV-2 IgG dynamic. J Microbiol Immunol Infect. 53(3):485-487. Scopus number of citations:41, 5 year IF:5.3
- Tsai HP*, Yeh CS, Lin IT, Ko WC, Wang JR. 2020 Jul. Increasing Cytomegalovirus Detection Rate from Respiratory Tract Specimens by a New Laboratory-Developed Automated Molecular Diagnostic Test. Microorganisms. 16;8(7):1063. Scopus number of citations:3, 5 year IF:4.8. (First and Corresponding author)
- Liu PY, Tsai YS, Chen PL, Tsai HP, Hsu LW, Wang CS, Lee NY, Huang MS, Wu YC, Ko WC, Yang YC, Chiang JH, Shen MR. 2020 Oct. Application of an Artificial Intelligence Trilogy to Accelerate Processing of Suspected Patients With SARS-CoV-2 at a Smart Quarantine Station: Observational Study. J Med Internet Res. 14;22(10):e19878. Scopus number of citations:5, 5 year IF:7.6
- Shen CF, Ho TS, Wang SM, Liao YT, Hu YS, Tsai HP, Chen SH. 2020 Oct; The cellular immunophenotype expression of influenza A virus and influenza B virus infection in children. Clin Immunol. 219:108548. Scopus number of citations:2, 5 year IF:5.7
- Huang SW, Tsai HP, Hung SJ, Ko WC, Wang JR. 2020 Dec. Assessing the risk of dengue severity using demographic information and laboratory test results with machine learning. PLoS Negl Trop Dis. 23;14(12):e0008960. Scopus number of citations:21, 5 year IF:4.1
- Kuo CW, Wang SY, Tsai HP, Su PL, Cia CT, Lai CH, Chen CW, Shieh CC, Lin SH. 2021 Mar. Invasive pulmonary aspergillosis is associated with cytomegalovirus viremia in critically ill patients - A retrospective cohort study. J Microbiol Immunol Infect. 31:S1684-1182(21)00057-8. Scopus number of citations:9, 5 year IF:5.3
- Sitjar J, Liao JD, Lee H, Tsai HP, Wang JR, Liu PY. 2021 Jun 1; Challenges of SERS technology as a non-nucleic acid or -antigen detection method for SARS-CoV-2 virus and its variants. Biosens Bioelectron. 181:113153. Scopus number of citations:50, 5 year IF: 10.8
- Liao YT, Tsai HP (co-first author), Wang SM, Chen SH. 2021 Sep 9; Clinical and Immune Responses of Peripheral Chemical Sympathectomy in Enterovirus 71 Infection. Front Immunol. 12:700903. Scopus number of citations:2, 5 year IF: 8.0
- Cia CT, Lin IT, Lee JC, Tsai HP, Wang JR, Ko WC. 2021 Oct 8; Respiratory viral infections in pragmatically selected adults in intensive care units. Sci Rep. 11(1):20058. Scopus number of citations:5, 5 year IF:4.9
- Sitjar J, Xu HZ, Liu CY, Wang JR, Liao JD, Tsai HP, Lee H, Liu BH, Chang CW. 2022 Feb 8; Synergistic surface-enhanced Raman scattering effect to distinguish live SARS-CoV-2 S pseudovirus. Anal Chim Acta. 1193:339406. Scopus number of citations:9, 5 year IF: 5.9
- Hung SJ, Tsai HP, Wang YF, Ko WC, Wang JR, Huang SW. 2022 Feb 10; Assessment of the Risk of Severe Dengue Using Intrahost Viral Population in Dengue Virus Serotype 2 Patients via Machine Learning. Front Cell Infect Microbiol. 12:831281. Scopus number of citations:2, 5 year IF:5.9
- 蔡慧頻*、李南瑤。呼吸道病毒感染之實驗診斷。感控雜誌 2022:32:107-116。Scopus number of citations:0, 5 year IF: non SCI paper
- Jhou YR, Wang CH, Tsai HP, Shan YS, Lee GB. 2022 May 1; An integrated microfluidic platform featuring real-time reverse transcription loop-mediated isothermal amplification for detection of COVID-19. Sens Actuators B Chem. 358:131447. Scopus number of citations:21, 5 year IF: 7.2
- Cheng D, Huang SW, Chin WX, Hung SJ, Tsai HP, Chu JJH, Chao CH, Wang JR. 2022 Jul 5; Impact of Intrahost NS5 Nucleotide Variations on Dengue Virus Replication. Front Microbiol. 13:894200. Scopus number of citations:2, 5 year IF:6.2
- Tsai YS, Wang CH, Tsai HP, Shan YS, Lee GB. 2022 Aug 1; Electromagnetically-driven integrated microfluidic platform using reverse transcription loop-mediated isothermal amplification for detection of severe acute respiratory syndrome coronavirus 2. Anal Chim Acta. 1219:340036. Scopus number of citations:6, 5 year IF:5.9
- Lin TY, Chi H, Kuo CY, Tsai HP, Wang JR, Liu CC, Shen CF. 2022 Sep 13; Outbreak of respiratory syncytial virus subtype ON1 among children during COVID-19 pandemic in Southern Taiwan. J Microbiol Immunol Infect. S1684-1182(22)00144-X. doi: 10.1016/j.jmii.2022.08.015. PMID: 36137926. Scopus number of citations:4, 5 year IF:5.3
- Wang LC, Tsai HP (co-first author), Chen SH, Wang SM. 2022 Oct 20; Therapeutics for fulminant hepatitis caused by enteroviruses in neonates. Front Pharmacol. 13:1014823. Scopus number of citations:2, 5 year IF:6.1
- Cheng D, Chiu YW, Huang SW, Lien YY, Chang CL, Tsai HP, Wang YF, Wang JR. 2022 Oct 20; Genetic and Cross Neutralization Analyses of Coxsackievirus A16 Circulating in Taiwan from 1998 to 2021 Suggest Dominant Genotype B1 can Serve as Vaccine Candidate. Viruses. 14(10):2306. doi: 10.3390/v14102306. PMID: 36298861; PMCID: PMC9608817. Scopus number of citations:2, 5 year IF:4.8
- Lee YR, Tsai HP*, Yeh CS, Fang CY, Chan MWY, Wu TY, Shen CH. 2022 Dec 29; RNA Interference Approach Is a Good Strategy against SARS-CoV-2. Viruses. 15(1):100. doi: 10.3390/v15010100. PMID: 36680140; PMCID: PMC9862891. Scopus number of citations:2, 5 year IF:4.8.
(Co-corresponding author)
- Tsai CS, Chen PL, Lee NY, Tsai HP, Huang SH, Chen SY, Tang YW, Lin YC, Tsai PF, Mao LW, Su SL, Wang JL, Ko WC. 2023 Apr; Characteristics of rectal chlamydia among men who have sex with men in southern Taiwan, 2020-2022: An emerging threat of rectal lymphogranuloma venereum L2b. J Microbiol Immunol Infect. 56(2):408-415. doi: 10.1016/j.jmii.2023.01.007. PMID: 36682913. Scopus number of citations:2, 5 year IF:5.3
- Sitjar J, Liao JD, Lee H, Tsai HP, Wang JR, Chen CH, Wang H, Liu BH. 2023 May 22; Detection of live SARS-CoV-2 virus and its variants by specially designed SERS-active substrates and spectroscopic analyses. Anal Chim Acta. 1256:341151. https://doi.org/10.1016/j.aca.2023.341151 Scopus number of citations:2, 5 year IF:5.9
- Tsai HP*, Lin CW, Lin YJ, Yeh CS, Shan YS. 2023 Jun 21; Novel Software for High-level Virological Testing: Self-Designed Immersive Virtual Reality Training Approach. J Med Internet Res. 25:e44538. doi: 10.2196/44538. PMID: 37342081; PMCID: PMC10337313. Scopus number of citations:0, 5 year IF: 7.6. (First and Corresponding author)
- Wu HB, Wang CH, Chung YD, Shan YS, Lin YJ, Tsai HP*, Lee GB. 2023 Sep 15; Highly-specific aptamer targeting SARS-CoV-2 S1 protein screened on an automatic integrated microfluidic system for COVID-19 diagnosis. Anal Chim Acta. 1274:341531. doi: 10.1016/j.aca.2023.341531. PMID: 37455073; PMCID: PMC10282962. Scopus number of citations:1, 5 year IF: 5.9. (Co-corresponding author)
- Kuo JY, Yeh CS, Wang SM, Chen SH, Wang JR, Chen TY, Tsai HP*. 2023 Aug; Acyclovir-resistant HSV-1 isolates among immunocompromised patients in southern Taiwan: Low prevalence and novel mutations. J Med Virol. 95(8):e28985. doi: 10.1002/jmv.28985. PMID: 37505438. Scopus number of citations:1, 5 year IF:8.5. (Corresponding author)
- Lin YJ, Wang LC, Tsai HP (co-first author), Chi CY, Chang CP, Chen SH, Wang SM. 2023 Oct 15; Antiviral and immunoregulatory effects of curcumin on coxsackievirus B3-infected hepatitis. Virus Res. 336:199203. doi: 10.1016/j.virusres.2023.199203. Epub 2023 Sep 1. PMID: 37625648; PMCID: PMC10485155. Scopus number of citations:0, 5 year IF:4.0
- Lee H, Liao JD, Tsai HP , Chen CH, Sitjar J, Fu WE, Lin FH. 2024 Jan 44. Label-free SERS method with size-matched selectivity for analytes of varying sizes. Surfaces and Interfaces.2024 Jan 44:103821. https://www.sciencedirect.com/science/article/pii/S2468023023011835 Scopus number of citations:0, 5 year IF:5.8
Chiu CH, Wang CH, Lin YJ, Tang CC, Peng WJ, Huang WY, Shan YS, Tsai HP*, and Lee GB. 2024 Simultaneous detection of SARS-CoV-2 and influenza A/B viruses on an electromagnetically-driven, integrated microfluidic system, Sensors and Actuators: B, accepted for publishing, 2024. 5 year IF:7.2 (Co-corresponding author).
研討會論文
- Kuo PH, Tsai HP, Yan JJ, Wang SM, Liu CC, Su IJ, Wang JR. 1998 Oct. 25 Enterovirus epidemic and typing analysis in Tainan, 1998. The 1998 annual meeting of the Chinese Society of Medical Technology, Taipei, Taiwan,.
- Tsai HP, Lai YJ, Wang YF, Liu CC, Su IJ, Huang KY, Wang JR. 1998. Nov. 26-30 Comparison on identification of enterovirus 71 and coxsackievirus A16. The 32th annual meeting of the Chinese Society of Microbiology, Taipei, Taiwan. Abstract V-3. CSM-87.
- Wang JR, Tsai HP, Chen PF, Lai YJ, Su IJ. 1999 Aug. 9-13. Laboratory diagnosis and genetic analysis of 1998 enterovirus 71 isolates in Taiwan. XIth International Congress of Virology, Sydney, Australia,
- Chen PF, Yan JJ, Lai YR, Tsai HP, Su IJ, Wang JR. 1999 Oct. 22-24. Rapid identification of enterovirus 71 and coxsackievirus A16 by RT-PCR. The 4th Chinese Laboratory Medicine Conference, Taipei, Taiwan.
- Wang JR, Yan JJ, Chen PF, Tsai HP, Su IJ. 2000. Rapid identification of enterovirus 71 and coxsackievirus A16 by RT-PCR. The 16th Clinical Virology Symposium, Clearwater Beach, Florida, April 30-May 3. Abstract M26.
- Kuo PH, Tsai HP, Chen PF, Yu JS, Tuan YC, Wang JR. 2000. Analysis of enterovirus 71 isolated from 1998 to 2000. The 34th annual meeting of the Chinese Society of Microbiology, Taipei, Taiwan, Dec. 3.
- Tsai HP, Yan JJ, Wang JR. 2000. Comparison of primer sets for detection of enterovirus 71 from clinical specimens by RT-PCR. The 34th annual meeting of the Chinese Society of Microbiology, Taipei, Taiwan, Dec. 3.
- Wang JR, Tuan YC, Chen PF, Yu JS, Tsai HP, Kuo PH. 2001. Change of major genotype of enterovirus 71 in outbreaks of hand-foot-and mouth disease in Taiwan between 1998 and 2000. The 17th Clinical Virology Symposium, Clearwater Beach, Florida, April 29-May 2. Abstract S43.
- Tsai HP, Huang SW, Kuo PH, Wang JR. 2001. Echovirus 30 associated with outbreak of aseptic meningitis in Taiwan in 2001. The 2001 annual meeting of the Chinese Society of Medical Technology, Taipei, Taiwan, Oct. 21.
- Huang SW, Tsai HP, Kuo PH, Wang JR. 2001. Genetic analysis of echovirus associated with outbreak of aseptic meningitis in Taiwan in 2001. The 35th annual meeting of the Chinese Society of Microbiology, Taipei, Taiwan, Dec. 16.
- Wang JR, Tsai HP, Huang SW, Kuo PH. 2002. Echovirus 30 associated with outbreak of aseptic meningitis in Taiwan in 2001. The 18th Clinical Virology Symposium, Clearwater Beach, Florida, April 28- May 1.
- Wang JR, Tsai HP, Huang SW, Kuo PH, Liu CC. 2002. Molecular analysisofechovirus30 associated with outbreak of aseptic meningitis in Taiwan in 2001. XIIth International Congress of Virology, Paris, France, July 27-Aug. 1.
- Huang SW, Tsai HP, Kuo PH, Wang JR. 2002. Analysis of echovirus 6 associated with outbreak of aseptic meningitis in Taiwan in 2001. The 2002 annual meeting of the Chinese Society of Medical Technology, Taipei, Taiwan, Nov. 3.
- Tsai HP, Huang SW, Kuo PH, Wang JR. 2002. Molecular evolution of influenza A/H3N2 viruses in southern Taiwan during 1999-2002.The 36th annual meeting of the Chinese Society of Microbiology, Taipei, Taiwan, Dec. 15.
- Tsai HP, Huang SW, Kuo PH, Liu CC, Wang JR. 2003. Screening of amantadine-resistant influenza A virus in Southern Taiwan. Current status & challenge of infectious disease in Asia, NHRI/NCKU, Feb. 21-22.
- Huang SW, Hsu YW, Tsai HP, Kuo PH, Liu CC, Wang JR. 2003. Genetic analysis of coxsackievirus A10 associated with herpangina outbreak in Taiwan. Current status & challenge of infectious disease in Asia, NHRI/NCKU, Feb. 21-22.
- Wang JR, Tsai HP, Kuo PH, Wang SM, Liu CC. 2003. Laboratory-supported influenza surveillance in southern Taiwan sentinel general practices from 1999 to 2002. Options for Influenza Control V, Okinawa, Japan, Oct. 7-11.
- Tsai HP, Chou WB, Hsu YW, Kuo PH, Wang JR. 2003. Comparison of three commercial rapid diagnosis kits and realtime RT-PCR for rapid detection of influenza virus from clinical specimens. The 37th annual meeting of the Chinese Society of Microbiology, Taichung, Taiwan, Dec. 7.
- Wang JR, Huang SW, Tsai HP, Kuo PH. 2004. Molecular analysis of an echovirus 6 associated outbreak of aseptic meningitis. The 20th Annual Clinical Virology Symposium, Clearwater Beach, Florida, April 25- 28.
- Wang JR, Tsai HP, Huang SW, Kuo PH, Liu CC. 2005. Genetic and antigenic characterization of influenza B viruses isolated in Taiwan from 1998 to 2004. XIII International Congress of Virology. San Francisco, California, July 23-28.
- Tsai HP, Wu FL, Huang SW, Liu CC, Wang JR. 2006. Typing and genetic analysis of echovirus 18 associated aseptic meningitis in Taiwan in 2006.The 40th annual meeting of the Chinese Society of Microbiology, Taipei, Taiwan, Nov. 18.
- Tsai HP, Wu FL, Huang SW, Kuo PH, Liu CC, Wang JR. 2007. Laboratory diagnosis and genetic analysis of echovirus 18 associated aseptic meningitis in Taiwan in 2006.The 23th Annual Clinical Virology Symposium and annual meeting Pan American Society for Clinical Virology, Clearwater Beach, Florida, April 29- May 2.
- Kung YH, Tsai HP, Kuo PH, Wang SY, Ko CW, Yan JJ, Wang JR. 2009. Evaluation of two rapid antigen tests for detection of influenza virus. The 2009 annual meeting of the Chinese Society of Medical Technology, Taipei, Taiwan, Nov. 8, 2009.
- Kuo PH, Wang HI, Tsai HP, Kung YH, Ko CW, Lee PC, Lin YJ, Wang JR. 2010. Establishment of a routine monitoring assay of polyomavirus BK in a clinical laboratory. Cross-strait Laboratory Medicine Symposium in 2010. Oct. 30-31.
- Kung YH, Kuo PH, Tsai HP, Ko CW, Wang HY, Chien ML, Chen HM, Yan JJ, Wang JR. 2011. Reduction in the overall contamination rate for virus culture. Fourth Asia-Pacific City Forum of Biomedical Laboratory Science. Tainan, Taiwan. April 30-May 1.
- Tsai HP, Wang SY, Kuo PH, Ko CW, Kung YH, Yan JJ, Wang JR. 2011. Evaluation of different rapid molecular diagnosis methods in detection of pandemic influenza type A virus (pH1N1). Forth Asia-Pacific City Forum of Biomedical Laboratory Science. Tainan, Taiwan. April 30-May 1. Received Distinguished Paper Award-Poster Presentation.
- Lin YT, Tsai HP, Kuo PH, Lin CW, Wang JR. 2012. Analysis of coxsackievirus A9 isolated from 2007 to 2011. The 2012 annual meeting of the Taiwan Society of Laboratory Medicine, Taipei, Taiwan, Nov. 4.
- Hung SJ, Huang SW, Tsai HP, Kuo PH, Wang JR. 2013. Epidemiology and genetic analysis of 2009 pandemic H1N1 influenza viruses from 2009 to 2012 in Taiwan. The 29th Clinical Virology Symposium, Daytona Beach, Florida, April 26- May 1.
- Wang JR, Chang CL, Tai CH, Kuo PH, Tsai HP. 2013. Molecular epidemiology of enterovirus 71 from 1998 to 2012 in Taiwan. The 32nd annual meeting of the American Society for Virology, The Pennsylvania State University, July 20-24.
- Wang SL, Kuo PH, Tsai HP, Wang JR. 2013. High incident adenoviral co-infections along with repeated infections revealed via a decade of molecular epidemiology study. The 32nd annual meeting of the American Society for Virology, The Pennsylvania State University, July 20-24.
- Tsai HP, Lin IT, Kuo PH, Ko CY, Cai YY, Yan JJ, Wang JR. 2013. Evaluation of commercial realtime PCR assays for quantification of Epstein-Barr virus DNA in plasma. The 2013 annual meeting of the Chinese Society of Medical Technology, Taipei, Nov. 2.
- Ko CY, Tsai HP, Kuo PH, Lin IT, Cai YY, Yan JJ, Wang JR.2013.Evaluation of Commercial Assays for Detection of Toxigenic Clostridium difficile Toxin in Stool Specimens.2013 3rd International Symposium on Infectious Disease and Signal Transduction, Tainan, Taiwan, Nov 16-17.
- Cai YY, Tsai HP, Kuo PH, Lin IT, Ko CY, Yan JJ, Wang JR. 2013. Respiratory syncytial virus infections among young children from 2009 to 2013 in southern Taiwan. The 22th annual meeting of Taiwan Society of Microbiology, Taipei, Taiwan, Dec. 15.
- Tsai HP, Kuo PH, Tsai YY, Lin IT, Ko CY, Tsai HN, Yan JJ, Wang JR. 2014. Comparison of Two Automated and Standardized CMV Viral Load Assays. Cross-strait laboratory medicine symposium in 2014. Aug 23~24.
- Tsai HP, Kuo PH, Tsai YY, Lin IT, Ko CY, Tsai HN, Chang KC, Wang JR. 2015. Evaluation of commercial In Vitro Diagnostics Dengue virus antibody rapid test. The 24th annual meeting of Taiwan Society of Microbiology, Taipei, Taiwan, Dec 14-15.
- Lin IT, Tsai HP, Kuo PH, Tsai YY, Ko CY, Tsai HN, Chang KC, Wang JR. 2016. Molecular epidemiology analysis of Echovirus in a cluster outbreak of aseptic meningitis. The 8th Asia-Pacific Forum of Medical Laboratory Science. Taichung, Taiwan, April16-17.
- Tsai HP , Tsai YY, Kuo PH, Lin IT, Ko CY, Tsai HN, Chen JC, Chang KC, Chen TY, Wang JR. 2016. Establish standardized cytomegalovirus viral load assays for monitoring treatment outcome in bone marrow or hematopoietic stem cell transplant recipients. The 8th Asia-Pacific Forum of Medical Laboratory Science. Taichung, Taiwan, April 16-17.
- Tsai HP , Tsai YY, Kuo PH, Lin IT, Ko CY, Tsai HN, Chen JC, Chang KC ,WC Ko, Wang JR. 2016. Validation and Application of a Commercial Quantitative Real-Time Reverse Transcriptase-PCR Assay in Investigation of a Large Dengue Virus Outbreak in Southern Taiwan. The 2016 annual meeting of the Chinese Society of Medical Technology, Taipei, Nov. 26-27.
- Lin IT, Tsai HP, Tsai YY, Ko CY, Tsai HN, Hou CM, Chang KC, Wang JR. 2017. Evaluate InBios Dengue NS1 DetectTM Kit for Detection of Dengue NS1 Antigen. The 9th Asia-Pacific Forum of Medical Laboratory Science. Taoyuan, Taiwan, April 15-16.
- Ko CY, Tsai HP, Kuo PH, Lin IT, Cai YY, Tsai HN, Hou CM, Chang KC, Wang JR. 2017. Analysis of Influenza Virus Epidemics, Severe and Death Cases from 2015 to 2016. The 9th Asia-Pacific Forum of Medical Laboratory Science. Taoyuan, Taiwan, April 15-16.
- Tsai HP, Kuo JY, Wang JR. 2017. Wang Analysis of antiviral resistance of herpes simplex virus from recurrent infections. The 9th Asia-Pacific Forum of Medical Laboratory Science. Taoyuan, Taiwan, April 15-16
- Tseng CJ, Tsai HP, Kuo PH, Tsai YY, Lin IT, Jen-Ren Wang JR. 2018. Improve the effectiveness of reporting in viral isolation for monitoring community viral activity by PDCA strategy. The 9th Asia-Pacific Forum of Medical Laboratory Science. April 14-16. Kaohsiung
- Tsai HP*, Lin IT, Yeh CS, Tsai YY, Wang JR. 2018. Rapid and ELISA tests for dengue diagnosis during dengue virus type 2 epidemic in TAIWAN. ASM Clinical Virology Symposium, May 6-9. West Palm beach, Florida, USA
- Lin IT, Tsai HP, Cia CT, Ko WC, Wang JR. 2018. Investigation of Multiple Respiratory Pathogens of Intensive Care Unit patients Using FilmArray Respiratory Panel. The 26th annual meeting of Taiwan Society of Microbiology, Taipei, Taiwan
- Tsai HP*, Yeh CS, Lin IT, Wang JR. 2018. Establish and Evaluate New Automated Molecular Diagnosis Systems for Detection of Human Cytomegalovirus in Various Clinical Specimens. the 2018 annual meeting of Taiwan Society of Laboratory Medicine in Taipei, Taiwan. (3~4 November 2018) (DP0318)The 2018 annual meeting of Taiwan Society of Laboratory Medicine, Taipei, Nov. 26-27. (Poster award)
- Chen PS, Tsai HP, Tsai YY, Lin IT, Chang KC, Wang JR. 2019. Comparison of two real-time PCR instruments in detection of Human T-lymphotropic virus type I. The 11th Asia-Pacific Forum of Medical Laboratory Science. Taichung, Taiwan, April 13-14
- Kung YH, Kuo PH, Lin IT, Tsai YY, Chen PS, Wang JR, Tsai HP*. 2019. Use risk assessment to improve the failure of laboratory developed viral molecular assays. The 11th Asia-Pacific Forum of Medical Laboratory Science. Taichung, Taiwan, April 13-14. (Poster award)
- Lin IT, Cia CT, Tsai PF, Ko WC, Wang JR, Tsai HP*. 2019.Investigation of Multiple Pathogen Detection Panel for the Identification of Microbial Agents in Cerebrospinal Fluid (CSF),Taiwan Society of Virology. Taipei, Taiwan. Oct. 26
- Tsai HP*, Lin IT, Yeh CS, Chen PS, Kung YH, Wang JR. 2019. Comparison of two new fully automated nucleic acid extraction combined realtime PCR assays in quantitation of Epstein-Barr virus. Taiwan Society of Virology. Taipei, Taiwan, Oct. 26
- Tsai HP*, Lin CW, Lin IT, Yeh CS, Liu SM, Adhi EA, Luthfan Fauza, Lee FY, Shi YC.2020. Application Self-Developed Virtual Reality Teaching Software for Cognition and Practical Skills Training on High-Level Technology of Clinical Virology. The 2020 annual meeting of Taiwan Society of Laboratory Medicine, Taipei, Nov. 7-8. (oral mini-E-poster)
- Kuo JY, Yeh CS, Kuo YT, Wang JR, Hou YC, Tsai HP* . 2020. Drug Resistant Screening and Investigation of Y248D Mutation on Thymidine Kinase among Immunocompromised Patients with HSV-1 infections. Cross-straitLaboratory Medicine Symposium in 2020, Taichung, Dec. 5-6. (poster)
- Sian L, Lin IT, Yeh CS, Tsai YY, Kung YH, Chen PS, Tsai HP*. 2022. Using automated nucleic acid molecular tests to detect viruses in ocular chamber fluid of patients. The 13th Asia-Pacific Forum of Medical Laboratory Science. Tainan, Taiwan, Augest 13-14
- Lin YJ, Sian L, Tsai HP*. 2022. Evaluation of Commercial Rapid Antigen Test for SARS-CoV-2 Infection. The 2022 annual meeting of Taiwan Society of Laboratory Medicine, Taipei, Nov. 5-6
- Tsai HP*, Lin YJ, Chen CJ, Huang CY, Wang JR. 2022. Comparison of Direct Immunofluorescent Assay and Rapid Molecular Diagnostic Test for Respiratory Syncytial Virus Infection. The 2022 annual meeting of Taiwan Society of Laboratory Medicine, Taipei, Nov. 5-6
- Tsai CS, Wang JL, Chen SY, Lin YC, Lin YJ, Tsai PF, Tsai HP, Ko WC. 2023. Asymptomatic enteric pathogens other than rectal gonorrhea and chlamydia among men who have sex with men: a cross-sectional surveillance, 2019-2022. The 2023 annual meeting of the Infectious Diseases Society of Taiwan, Taipei, March 18-19
- Tsai YY, Tsai HP, Lin YJ, Chiang CH, Wang JR. 2023. Risk assessment of Isolation and identification of virus by Failure Mode and Effects Analysis. The 14th Asia-Pacific Forum of Medical Laboratory Sciences held on 22–23 April 2023, Taichung, Taiwan. (The Distinction Award-E-poster Presentation
- Lin YJ, Tsai HP*. 2023. Improving the quality of immunofluorescence staining for adenovirus antigen detection. The 2023 annual meeting of Taiwan Society of Laboratory Medicine, Taichung, Nov. 18-19
- Tsai HP, Yeh CS, Huang SW, Wang SM, Wang JR, Chen SH. 2023. Epidemiology and Phylogenetic Analysis of Emerging Pediatric Human Enterovirus B Infections in Southern Taiwan. The 2023 annual meeting of Taiwan Society of Laboratory Medicine, Taichung, Nov. 18-19
- Tsai CS, Wang JL, Lee NY, Chen PL, Lin YJ, Tsai HP, Huang HH, Su SL, Mao LW, Ko WC. 2023. Predominance of lymphogranuloma venereum L2b sequence type ST53 and a novel ST39 strain among men who have sex with men in southern Taiwan, 2020-2023. 2023 International Conference on Emerging Infectious Diseases. Epidemic Prevention Scientific Research Center, NCKU.Tainan, Nov. 25
研究計畫
成大醫院醫療科技研究計劃主持人:
- 新冠疫情前後之流感住院病患克流感抗藥性篩檢 (NCKUH-11308002)
- 創建臨床病毒分生高階檢驗機台(BD MAX)操作技能之3D虛擬實境及其學習模式(NCKUH-11208002)
- 南台灣幼兒致命性B型腸病毒流行病學與分子演化分析 (NCKUH-11108001)
- 免疫功能低下病患單純皰疹第一型變異病毒株的抗藥性機制之研究 (NCKUH-11008006)
- 免疫功能低下病人之單純疱疹病毒抗藥性分析 (NCKUH-10906006)
- 分析台南第二型登革病毒疫情之二次感染盛行率與其疾病嚴重度的病毒決定因子 (NCKUH-10806001)。
- 建立與評估全自動新分生平台以檢測各式臨床檢體中之巨細胞病毒 (NCKUH-10708001) 。
- 登革病毒早期診斷試劑組及患者多重病原體感染之分析研究 (NCKUH-10608002)。
- 單純疱疹病毒引發重複性感染的臨床病毒株之抗藥性分析 (NCKUH-10502002)。
- 建立巨細胞病毒核酸量方法之標準化以做為骨髓或週邊血液幹細胞移植病人治療預後之評估(NCKUH-10404005)。
- 快速分子檢測新型流感病毒方法之評估 (NCKUH-9902019)。
院外研究計劃主持人 (農業部/農委會-計畫主辦人):
1.運用自行開發虛擬實境軟體於高階臨床病毒檢驗技能訓練 (教育部教學實踐計畫-H110-A119)
2. 使用針對 SARS-CoV-2 的小干擾 RNA 作為預防和治療策略 (戴德森醫療財團法人嘉義基督教醫院CYC110011)
3. 強化非洲豬瘟早期預警之檢驗量能計畫(農業部<112-管理-18.1-非洲豬瘟-01>)
4. 強化非洲豬瘟早期預警之檢驗量能計畫 (農委會<111-管理-18.1-非洲猪瘟-01>)
5. 強化非洲豬瘟早期預警之檢驗量能計畫 (農委會<110-管理-8.11-非洲猪瘟-01>)
6. 非洲豬瘟初篩實驗室建置工作計畫 (農委會<109-救助調整-檢-08>)
7. 非洲豬瘟初篩實驗室建置工作計畫 (農委會<108-救助調整-檢-07 (追加)>主辦、參與國際會議
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