開授課程

• 大學部
  • 上學期
  • 普通生物學、醫技導論、專題研究實驗
  • 下學期
    • 專題研究實驗
• 碩士班
  • 上學期
  • 下學期

學歷

• 國立成功大學基礎醫學研究所博士
• 國立成功大學分子醫學所碩士直升
• 國立成功大學生命科學系學士

經歷

• 國立成功大學醫學檢驗生物技術系 兼任助理教授 (2020/08~迄今) 
• 加州大學洛杉磯分校 訪問學者 (2020/01~2020/02) 
• 臺灣奈米生醫學會 秘書長 (2019/06~迄今) 
• 國立成功大學奈米醫學研究中心 助理研究員 (2019/01~迄今) 
• 國立成功大學奈米醫學研究中心 企劃組組長 (2018/04~迄今) 
• 國立成功大學矽谷創業培訓計畫 亮子點應材團隊 CEO (2017/01~2017/04) 
• 國立高雄科技大學水產養殖系 兼任助理教授 (2015/02~2019/01) 

實驗室研究方向

本實驗室主要研究方向在將各種新興跨領域技術 (奈米技術、電子顯微鏡、AI技術與微流道晶片等)導入生物醫學應用，例如利用原先作為太陽能產氫的石墨烯量子點奈米材料應用於光動力癌症治療及生醫診斷訊號的放大；利用特殊樣本載台設計使用電子顯微鏡觀察液態生物樣本；利用AI技術加速細菌藥敏性檢測；利用微流道晶片分析癌細胞的藥物敏感性。

指導學生

王玟琇(112級)

陳育萱(112級)

指導學生之特殊榮譽

2020國際奈米科技奧林匹亞(INO)國家代表隊選拔賽全國亞軍

生活照

無相關資料

專利

1. Method for determining treatment response of cells. 細胞治療反應的判斷方法 Wei-Lun Huang, Wu-Chou Su, Wei-Pang Chung, Hai-Wen Chen, Hsien-Chang Chang
2. Reaction system and using method thereof. 反應系統及該反應系統的使用方法 Wei-Lun Huang, Wu-Chou Su, Hai-Wen Chen, Yu-Min Yeh, Wei-Pang Chung, Te-Fu Yeh, Hsisheng Teng, Chiao-Yi Teng, Liang-Che Chen, Chung-Jen Chung
3. Method by use of particle separation of lateral dielectrophoresis, flow path device and capture structure. 利用側向介電泳分離粒子之方法、其流道裝置以及捕捉結構 I-Fang Cheng, Wu-Chou Su, Wei-Lun Huang, Yu-De Lin, Tzu-Ying Chen
4. Method and chip for capturing and analyzing biological particles by composite electromotive force. 以複合電動力捕捉並分析生物微粒的方法與晶片 I-Fang Cheng, Hsien-Chang Chang, Wu-Chou Su, Wei-Lun Huang
5. Molecular probe for signal amplification and kit and assay using the same. 可放大訊號的分子探針及其試劑組與使用方法 Wei-Lun Huang, Wu-Chou Su, Hai-Wen Chen, Wei-Pang Chung, I-Ting Chiang, Te-Fu Yeh, Hsisheng Teng, Laing-Che Chen
6. Non-metallic semiconductor quantum dot and method of carrying out chemical reaction or photoluminescence reaction by using the same. 非金屬半導體量子點及以其進行化學反應或光致發光反應的方法 Wei-Lun Huang, Wu-Chou Su, Hai-Wen Chen, Te-Fu Yeh, Hsisheng Teng, Chung-Jen Chung
7. Semiconductor quantum dot and method of carrying out chemical reaction or photoluminescence reaction by using the same. 半導體量子點及以其進行化學反應或光致發光反應的方法 Wei-Lun Huang, Wu-Chou Su, Hai-Wen Chen, Te-Fu Yeh, Hsisheng Teng, Chung-Jen Chung

技術轉移

無相關資料

期刊論文

1. Michael Tu, Jordan Cheng, Yi-Lin Chen, Wen-Chien Jea, Wan-Li Chen, Chien-Jung Chen, Chung-Liang Ho, Wei-Lun Huang, Chien-Chung Lin, Wu-Chou Su, Qianlin Ye, Josh Deignan, Wayne Grody, Feng Li, David Chia, Fang Wei, Wei Liao, David T.W. Wong, Charles M Strom. Electric Field Induced Release and Measurement (EFIRM): Characterization and technical validation of a novel liquid biopsy platform in plasma and saliva. Journal of Molecular Diagnostics 2020 Aug; 22(8): 1050-1062. (SCI; IF= 5.553)
2. Feng Li, Fang Wei, Wei-Lun Huang, Chien-Chung Lin, Liang Li, Macy M. Shen, Qingxiang Yan, Wei Liao, David Chia, Michael Tu, Jason H. Tang, Ziding Feng, Yong Kim, Wu-Chou Su, David T.W. Wong. Ultra-short circulating tumor DNA (usctDNA) in plasma and saliva of non-small cell lung cancer (NSCLC) patients. Cancers 2020 Jul; 12(8): 2041. (SCI; IF= 6.126)
3. Kundan Sivashnamugan*, Wei-Lun Huang* (*Equal Contribution First Author), Chen-Hsueh Lin, Jiunn-Der Liao, Chien-Chung Lin, Wu-Chou Su, Ten-Chin Wen. Bimetallic Nanoplasmonic Gap-mode SERS Substrate for Distinguishing Lung Normal and Cancer-Derived Exosomes. Journal of the Taiwan Institute of Chemical Engineers 2017 Nov; 80: 149-155. (SCI; IF= 4.794)
4. Wei-Lun Huang*, Yi-Lin Chen* (*Equal Contribution First Author), Szu-Chun Yang (Equal Contribution First Author), Chung-Liang Ho, Fang Wei, David T. Wong, Wu-Chou Su, Chien-Chung Lin. Liquid biopsy genotyping in lung cancer: ready for clinical utility? Oncotarget 2017 Mar; 8(11): 18590-18608.
5. Te-Fu Yeh, Wei-Lun Huang, Chung-Jen Chung, Hsin-Yu Chang, Chun-Yu Lin, Wu-Chou Su, Ching Cheng, Shean-Jen Chen, Hsisheng Teng. Elucidating quantum confinements in graphene oxide quantum dots for high-quality photoluminescence emissions. Journal of Physical Chemistry Letters 2016 Jun; 7(11): 2087-2092. (SCI; IF= 6.710)
6. Chien-Chung Lin, Wei-Lung Huang, Fang Wei, David T. Wong, Wu-Chou Su. Emerging platform using liquid biopsy to detect EGFR mutations in lung cancer. Expert Review of Molecular Diagnostics 2015 Nov; 15(11): 1427-1440. (Review Paper; Invited) (SCI; IF= 4.096)
7. Wei-Lung Huang, Fang Wei, David T. Wong, Chien-Chung Lin, Wu-Chou Su. The emergent landscape of detecting EGFR mutations using circulating tumor DNA in lung cancer. BioMed Research International 2015 Sep; 2015: 340732. (Review Paper; Invited) (SCI; IF= 2.276)
8. I-Fang Cheng, Wei-Lun Huang, Tzu-Ying Chen, Chien-Wei Liu, Yu-De Lin, Wu-Chou Su. Antibody-free isolation of rare cancer cells from blood based on 3D lateral dielectrophoresis. Lab on a Chip 2015 Jun; 15(14): 2950-2959. (Back Cover) (SCI; IF= 6.774)
9. Chien-Chung Lin, Hsuan-Heng Yeh, Wei-Lun Huang, Wu-Chou Su. Metformin enhances cisplatin cytotoxicity by suppressing Stat3 activity independently of the LKB1-AMPK-MTOR pathway. American Journal of Respiratory Cell and Molecular Biology 2013 Aug; 49(2): 241-250. (SCI; IF= 5.373)
10. Hao-Chen Wang, Hsuan-Heng Yeh, Wei-Lun Huang, Chien-Chung Lin, Wen-Pin Su, Helen H. W. Chen, Wu-Wei Lai, Wu-Chou Su. Activation of the signal transducer and activator of transcription 3 pathway up-regulates estrogen receptor-β expression in lung adenocarcinoma cells. Molecular Endocrinology 2011 Jul; 25(7): 1145-1158. (SCI; IF= 3.628)
11. Wei-Lun Huang, Hsuan-Heng Yeh, Chien-Chung Lin, Wu-Wei Lai, Jang-Yang Chang, Wen-Tsan Chang, Wu-Chou Su. Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established cancer cell lines and clinical isolated human cancer cells. Molecular Cancer 2010 Dec; 9: 309. (SCI; IF= 15.302)
12. Chien-Chung Lin*, Wei-Lun Huang* (*Equal Contribution First Author), Wen-Pin Su, Helen H. W. Chen, Wu-Wei Lai, Jing-Jou Yan, Wu-Chou Su. Single cell phospho-specific flow cytometry can detect dynamic changes of phospho-Stat1 level in lung cancer cells. Cytometry Part A 2010 Nov; 77A(11): 1008-1019. (SCI; IF= 3.124)
13. Wei-Shio Hor, Wei-Lun Huang, Yee-Shin Lin, Bei-Chang Yang. Cross-talk between tumor cells and neutrophils through the Fas (APO-1, CD95)/FasL system: human glioma cells enhance cell viability and stimulate cytokine production in neutrophils. Journal of Leukocyte Biology 2003 Mar; 73 (3): 363-368. (SCI; IF= 3.757)

專書

無相關資料

作品發表(含展演)

無相關資料

Other publications

無相關資料

主辦、參與國際會議

1. Wei-Lun Huang, Wu-Chou Su. Potential roles of cancer derived extracellular vesicles in lung cancer metastasis and progression. 2019 International Society for Extracellular Vesicles (ISEV) Annual Scientific Meeting, Kyoto, Japan.

2. Wei-Lun Huang, Kundan Sivashnamugan, Ten-Chin Wen, Wu-Chou Su. Identifying potential biomarkers for lung cancer from the cancer derived exosomes using the nano gap-mode surface-enhanced Raman scattering (SERS). 2018 International Society for Extracellular Vesicles (ISEV) Annual Scientific Meeting, Barcelona, Spain.

3. Wei-Lun Huang*, Kundan Sivashnamugan* (*Equal Contribution First Author), Ten-Chin Wen, Wu-Chou Su. Distinguishing lung normal and cancer-derived exosomes, the naturally occurring liposome-like vesicles, using SERS. Lipidomics and Bioactive Lipids in Metabolism and Disease, Tahoe City, USA.

4. Wei-Lun Huang, Wu-Chou Su. Detection of actionable EGFR mutations in secretory extracellular vesicles (EV) from non-small cell lung cancer patients. 21th World Congress on Advances in Oncology & 19th International Symposium on Molecular Medicine, Athens, Greece. (Invited Speech)

5. Wei-Lun Huang, Chien-Chung Lin, Shang-Rung Wu, Wu-Chou Su. The role of lung cancer derived extracellular vesicles in tumor progression. 2016 International Society for Extracellular Vesicles (ISEV) Annual Scientific Meeting, Rotterdam, the Netherlands.

6. Wei-Lun Huang, Chien-Chung Lin, Shang-Rung Wu, Wu-Chou Su. Lung cancer derived extracellular vesicles triggered oncogenic signals and increased vascular permeability in an autocrine/paracrine fashion. 2015 International Society for Extracellular Vesicles (ISEV) Annual Scientific Meeting, Washington DC, USA.

8. Wei-Lun Huang, Chien-Chung Lin, Wu-Chou Su. Evaluation of the roles of nanometer sized extracellular vesicles on lung cancer progression: biological functions and clinical applications. 2013 ISEV Workshop: EV isolation and Characterization, Budapest, Hungary. (Invited Speech, only 66 selected participants)

9. Wei-Lun Huang, Chien-Chung Lin, Wu-Chou Su. Evaluation of the roles of nanometer sized extracellular vesicles on lung cancer progression. 2013 International Society for Extracellular Vesicles (ISEV) Annual Scientific Meeting, Boston, USA.

10. Wei-Lun Huang, Chien-Chung Lin, Wu-Chou Su. Isolation of tumor associated exosomes from clinical samples using the ultra-filtration method. 2012 International Society for Extracellular Vesicles (ISEV) Annual Scientific Meeting, Gothenburg, Sweden.

11. Wei-Lun Huang, Hsuan-Heng Yeh, Wu-Chou Su. Stat3 positively regulates IL-6 expression in lung cancer cells. 2008 American Association for Cancer Research (AACR) Annual Meeting, San Diego, USA.

教學、研究國際交流

• 至國外學術機構訪問次數： UCLA訪問學者：2020/01-2020/02