個人資料

2018/04/04

郭保麟 教授
Pao-Lin Kuo
辦公室地點：醫學院4樓 (82-0447)
電子信箱： paolink@mail.ncku.edu.tw

開授課程

學歷

經歷

實驗室研究方向

歷年實驗室研究成員

林盈宏（基醫所畢業、博士後研究員）
郭永哲（基醫所畢業）、蘇美慈 (臨醫所畢業）

榮譽及獎勵

專利

無相關資料

技術轉移

無相關資料

期刊論文

  • Huang HB, Kuo PL, Chang JW, Jaakkola JJK, Liao KW, Huang PC. Longitudinal assessment of prenatal phthalate exposure on serum and cord thyroid hormones homeostasis during pregnancy - Tainan birthcohort study (TBCS). Science of Total Environment 2018,2015-1065 SCI
  • Huang JY, Yu PH, Li YC, Kuo PL. (corresponding author) NLRP7 contributes to in vitro decidualization of endometrial stromal cells. Reproductive Biology Endocrinology. 2017;15(1):66. doi: 10.1186/s12958-017-0286-x. SCI
  • Wang CY, Hong YH, Syu JS, Tsai YC, Liu XY, Chen TY, Su YM, Kuo PL, Lin YH, Teng YN. LRWD1 regulates microtubule nucleation and proper cell cycle progression in the human testicular embryonic carcinoma cells. Journal of Cellular Biochemistry. 2017; doi: 10.1002/jcb.26180. [Epub ahead of print ]SCI
  • Tsai YC, Tseng JT, Wang CY, Su MZ, Huang JY, Kuo PL. (corresponding author) Medroxyprogesterone acetate drives M2 macrophage differentiation toward a phenotype of decidual macrophage. Molecular and Cellular Endocrinology. 2017;452:74-83. SCI
  • Shen YR, Wang HY, Kuo YC, Shih SC, Hsu CH, Chen YR, Wu SR, Wang CY, Kuo PL . (corresponding author) SEPT12 phosphorylation results in loss of the septin ring/sperm annulus, defective sperm motility and poor male fertility. PLoS Genetics 20171(3): e1006631. doi: 10.1371/journal.pgen.1006631. SCI
  • Song XH, Hsu HK, Su MT, Chang TS, Su PY, Chen M, Kuo PL. (corresponding author) Euchromatic variant of 8q21.2 in twins. Taiwanese Journal of Obstetrics and Gynecology 2017;56:227-229. SCI
  • Chen TH, Tian X, Kuo PL, Pan HP, Wong LJC, Jong YJ. Identification of KLHL40 Mutations by Targeted Next Generation Sequencing Facilitated a Prenatal Diagnosis in a Family with 3 Consecutive Affected Fetuses with Fetal Akinesia Deformation Sequence. Prenatal Diagnosis 2016;36:492-495. SCI
  • Hsu PH, Li MC, Lee YC, Kuo PL, Guo YL. Polychlorinated biphenyls and dibenzofurans increased abnormal sperm morphology without alterations in aneuploidy: The Yucheng study. Chemosphere 2016;165:294-297. SCI
  • Lai TH, Wu YY, Wang YY, Chen MF, Wang P, Chen TM, Wu YN, Chiang HS, Kuo PL, Lin YH. SEPT12-NDC1 complexes are required for mammalian spermiogenesis. International Journal of Molecular Sciences 2016 17, 1911; doi:10.3390/ijms17111911. SCI
  • Huang PC, Tsai CH, Liang WY, Lee SS, Huang HB, Kuo PL (equal contribution to the 1st author). Early phthalates exposure in pregnant women is associated with alteration of thyroid hormones. PLoS One 2016; DOI:10.1371 /journal.pone. 0159398 SCI
  • Su MT, Tsai PY, Tsai HL, Chen YC, Kuo PL. miR-346 and miR-582-3p-regulated EG-VEGF expression and trophoblast invasion via matrix metalloproteinases 2 and 9. Biofactors 2016; doi: 10.1002/biof.1325. SCI
  • Solis MA, Wei YH, Chang CH, Yu CH, Kuo PL, Huang LLH. Hyaluronan upregulates mitochondrial biogenesis and reduces adenoside triphosphate production for efficient mitochondrial function in slow-proliferating human mesenchymal stem cells. Stem Cells 2016,34(10):2512-2524. doi: 10.1002/stem.2404.SCI
  • Su MT, Kuan LC, Chou YY, Tan SY, Kuo TC, Kuo PL (corresponding author). Partial trisomy of chromosome 21 without the Down syndrome phenotype. Prenatal Diagnosis 2016;36:1-4. SCI
  • Lin CY, Chen CY, Yu CH, Yu IS, Lin SR, Wu JT, Lin YH, Kuo PL, Wu JC, Lin SW. Human X-linked intellectual disability factor CUL4B is required for post-meiotic sperm development and male fertility. Scientific Reports 2016; 6:20227 | DOI: 10.1038/srep20227. SCI
  • Su MT, Huang JY, Hsai HL, Chen YC, Kuo PL (corresponding author). A common variant of PROK1 (V67I) acts as a genetic modifier in early human pregnancy through down-regulation of gene expression. International Journal of Molecular Science. 2016;17(2). pii: E162. doi: 10.3390/ijms17020162. SCI
  • Yeh CH, Kuo PL. Wang YY, Wu YY, Lin DY, Lai TH, Chiang HS, Lin YH. SEPT12/SPAG4/LAMINB1 complexes are required for maintaining the integrity of nuclear envelope in postmeiotic male germ cells. PLoS One 2015;10(3): e0120722. doi: 10.1371. SCI
  • Tsai MC, Chou YY, Wang JN, Wu JM, Huang CC, Kuo PL, Tsai YS. Type B interrupted aorta and hydrocephalus associated with mosaicism of a 1.37 Mb amplified cat eye syndrome critical region. Pediatrics and Neonatology 2016; 56:277-279. SCI
  • Kuo YC, Shen YR, Chen HI, Lin YH, Wang YY, Chen YR, Wang CY, Kuo PL (corresponding author). SEPT12 orchestrates the formation of mammalian sperm annulus by organizing SEPT12-7-6-2/-4 core complexes. Journal of Cell Science 2015;128(5):923-934. SCI
  • Tsai MC, Cheng HY, Su MT, Chen M, Kuo PL (corresponding author). Partial trisomy 8 mosaicism not detected by cultured amniotic fluid cells – A case report. Taiwanese Journal of Obstetrics and Gynecology 2014;54(4):598-601. SCI
  • Su MT, Lin SH, Chen YC, Kuo PL (corresponding author). Gene-gene interactions and risk of recurrent miscarriages in carriers of EG-VEGF and Prokineticin receptors polymorphisms. Fertility and Sterility 2014;102(4): 1071-1077. SCI
  • Su MT, Lin SH, Chen YC, Kuo PL (corresponding author). Gene-gene interactions and gene polymorphisms of VEGF and EG- VEGF gene systems in recurrent pregnancy loss. Journal of Assisted Reproduction and Genetics 2014;3(16):699-705. SCI
  • Tsai YC, Teng YN, Hung JH, Wu CH, Kuo YT, Kuo PL, Chiu CC, Huang B. Correlation between leucine rich domain and the stability of LRWD1 protein in human NT2/D1 cells. Advances in Medical Sciences 2014;59:266-272. SCI
  • Chen YY, Chuang PY, Chen CP, Chiu YH, Lo HF, Cheong ML. Huang JY, Kuo PL, Chen H. Functional antagonism between high temperature requirement protein A (HtrA) family members regulates trophoblast invasion. Journal of Biological Chemistry 2014;15(33):22958-68. SCI
  • Kuo PL, Hung YL, Hsieh CCJ, Lin BW, Lee JC, Hung LY. STK31 is a cell-cycle regulated protein that contributes to the tumorigenecity of epithelial cancer cells. PLoS One 2014;9(3);e93303. SCI
  • Chang CW, Hsu HK, Kao CC, Huang JY, Kuo PL (corresponding author). Prenatal diagnosis of Prader-Willi syndrome and Angelman syndrome for cases with suspicious deletion of chromosomal region 15q11～13. International Journal of Gynecology and Obstetrics 2014;125:18-21. SCI
  • Hsu HK, Su MT, Chen M, Yen P, Kuo PL (corresponding author). Two Y chromosomes with duplication of the distal arm including the entire AZFc region. Gene 2014;536:444-448. SCI
  • Wu CH, Yang JG, Chang YJ, Hsu CC, Kuo PL (corresponding author). Screening of a Panel of Steroid-Related Genes Showed Polymorphisms of Aromatase Genes Confer Susceptibility to Advanced-Stage Endometriosis in the Taiwanese Han Population. Taiwanese Journal of Obstetrics and Gynecology 2013;52(4):485-492. SCI
  • Kuan LC, Su MT, Chen M, Kuo PL, Kuo TC. Non-mosaic isodicentric Y chromosome resulting from breakage and fusion at the Yq pseudo-autosomal region in a fetus. Journal of Assisted Reproduction and Genetics 2013;30:1559-1562. SCI
  • Kuo PL, Chiang HS, Wang YY, Kuo YC, Cheng MF, Yu IS, Teng YN, Lin SW, Lin YH. SEPT12-microtubules complexes are required for sperm-head and sperm-tail formation. International Journal of Molecular Sciences 2013;14:22102-22116. SCI
  • Kuan LC, Su MT, Chen M, Kuo PL, Kuo TC. A dicentric Y chromosome resulting from pericentric inversion between the centromere and Yq heterochromatin, Taiwanese Journal of Obstetrics and Gynecology 2013;52(3):443-5. SCI
  • Su MT, Lin SH, Chen YC, Wu LW, Kuo PL (corresponding author). Prokineticin Receptor Variants (PKR1-I379V and PKR2-V331M) Are Protective Genotypes in Human Early Pregnancy. Reproduction 2013;14;146(1):63-73. SCI
  • Kuan LC, Su MT, Kuo PL, Kuo TC (corresponding author). Direct duplication of Y chromosome with normal phenotype – incidental finding in two cases. Andrologia 2013;45:140-144. SCI
  • Tsai YT, Chao HCA, Chung CL, Liu XY, Lin YM, Liao PC, Pan HA, Chiang HS, Kuo PL, Lin YH (corresponding author). Characterization of 3-hydroxyisobutyrate dehydrogenase, HIBADH, as a sperm-motility marker Journal of Assisted Reproduction and Genetics. Journal of Assisted Reproduction and Genetics 2013;30:505-512, SCI
  • Su MT, Lee IW, Liang YL, Chen JC, Sun HS, Chang FM, Kuo PL (corresponding author). Non-mosaic uniparental trisomy 16 presenting with asplenia syndrome and placental abruption. A case report and literature review. European Journal of Medical Genetics 2013;56:197-201. SCI
  • Lee KF, Hsu CS, Kuo PL, Chen JL, Jiang YH, Liu IY The identification of a spontaneous 47,XX,+21/46,XY chimeric fetus with male genitalia. BMC Medical Genetics 2013;13:85. SCI
  • Huang JY, Su MT, Lin SH, Kuo PL (corresponding author). A genetic study of NLRP2 and NLRP7 genes in idiopathic recurrent miscarriage. Human Reproduction 2013;28:127-134. SCI
  • Su MT, Lin SH, Chen YC, Kuo PL (corresponding author). Genetic association of ACE and PAI-1 genes in women with recurrent pregnancy loss A Systemic Review and Meta-Analysis. Thrombosis and Haemostasis 2013;109:8-15. SCI
  • Kuan LC, Su MT, Kuo PL, Kuo TC (corresponding author). Direct duplication of Y chromosome with normal phenotype – incidental finding in two cases. Andrologia 2013;45:140-144. SCI
  • Tsai YT, Chao HCA, Chung CL, Liu XY, Lin YM, Liao PC, Pan HA, Chiang HS, Kuo PL, Lin YH (corresponding author). Characterization of 3-hydroxyisobutyrate dehydrogenase, HIBADH, as a sperm-motility marker Journal of Assisted Reproduction and Genetics. Journal of Assisted Reproduction and Genetics 2013;30:505-512, SCI
  • Su MT, Lee IW, Liang YL, Chen JC, Sun HS, Chang FM, Kuo PL (corresponding author). Non-mosaic uniparental trisomy 16 presenting with asplenia syndrome and placental abruption. A case report and literature review. European Journal of Medical Genetics 2013;56:197-201. SCI
  • Lee KF, Hsu CS, Kuo PL, Chen JL, Jiang YH, Liu IY The identification of a spontaneous 47,XX,+21/46,XY chimeric fetus with male genitalia. BMC Medical Genetics 2013;13:85. SCI
  • Huang JY, Su MT, Lin SH, Kuo PL (corresponding author). A genetic study of NLRP2 and NLRP7 genes in idiopathic recurrent miscarriage. Human Reproduction 2013;28:127-134. SCI
  • Su MT, Lin SH, Chen YC, Kuo PL (corresponding author). Genetic association of ACE and PAI-1 genes in women with recurrent pregnancy loss A Systemic Review and Meta-Analysis. Thrombosis and Haemostasis 2013;109:8-15. SCI
  • Lee IW, Hsu HK, Lai YC, Kuo PL, Chang CM (corresponding author). Human sex ratio at amniocentesis and at birth in Taiwan. Taiwanese Journal of Obstetrics and Gynecology 2012;51:572-572. SCI
  • Teng YN, Chang YP, Tseng JT, Kuo PH, Lee IW, Lee MS, Kuo PL (corresponding author) A Single nucleotide polymorphism of DAZL gene promoter confer susceptibility to spermatogenic failure in the Taiwanese Han. Human Reproduction 2012;27:2857-2865. SCI
  • Lin YH, Wang YY, Chen HI, Kuo YC, Chiou YW, Lin HH, Wu CM, Hsu CC, Chiang HS, Kuo PL (corresponding author). SETPTIN12 genetic variants confer susceptibility to teratozoospermia. PLoS One 2012;7(3):e34011.SCI
  • Kuo YC, Lin YH, Chen HI, Wang YY, Chiou YW, Lin HH, Pan HA, Wu CM, Su SM, Hsu CC, Kuo PL (corresponding author). SEPT12 mutations cause male infertility with defective sperm annulus. Human Mutation 2012;33(4):710-719. SCI
  • Lee IW, Kuo PS, Su MT, Kuan LC, Hsu CH, Kuo PL (corresponding author) Quantitative train analysis suggests estrogen-related gene regulate sperm counts and motility. Human Reproduction (Epud ahead of reprint) SCI
  • Lin YH, Lin YM, Kuo YC, Wang YY, Kuo PL (corresponding author). Identification and characterization of a novel Rab GTPase-activation protein in spermatids. International Journal of Andrology (Epud ahead of reprint) SCI
  • Su MT, Lee IW, Chen YC, Kuo PL (corresponding author). Association of progesterone receptor polymorphism with idiopathic pregnancy loss in Taiwanese Han population. Journal of Assisted Reproduction and Genetics (Epud ahead of reprint) SCI
  • Lee IW, Chou YY, Hsu KF, Chou PY, Chen M, Kuo PL, Lin SJ. Complex chromosome rearrangement 46,XY,der(9)t(Y;9)(q12;p23) in a girl with sex reversal and mental retardation. Urology (Epud ahead of reprint) SCI
  • Lee IW, Kang L, Hsu HP, Kuo PL, Chang CM. Puerperal mastitis requiring hospitalization during a nine-year period. American Journal of Obstetrics and Gynecology (Epud ahead of reprint) SCI
  • Su MT, Lin SH, Lee IW, Chen YC, Kuo PL (corresponding author). Association of polymorphisms/haplotypes of the genes encoding vascular endothelial growth factor and its KDR receptor with recurrent pregnancy loss. Human Reproduction 2011;26:758-764. SCI
  • Yang CY, Huang TS, Lin KC, Kuo PL, Tsai PC, Guo YL. Menstrual effect among women exposed to polychlorinated biphenyls dibenzofurans. Environmental Research (accepted) SCI
  • Su MT, Lin SH, Lee IW, Chen YC, Hsu CC, Pan HA, Kuo PL (corresponding author). Polymorphisms of endocrine gland-derided vascular endothelial growth factor gene and its receptor gene are associated with recurrent pregnancy loss. Human Reproduction 2010;25:2923-2930. SCI
  • Lin YH, Chou CK, Huang YC, Yu IS, Pan HA, Lin SW, Kuo PL ( corresponding author). SEPT12 deficiency causes sperm nucleus damage and developmental arrest of preimplantation embryos. Fertility and Sterility 2011;95:363-365. SCI
  • Wu CH, Yang JG, Yang JJ, Lin YM, Tsai HD, Lin CY, Kuo PL (corresponding author). Androgen excess down-regulates connexin 43 in a human granulosa cell line. Fertility and Sterility 2010;94:2938-2941. SCI
  • Chao HCA, Lin YH, Kuo YC, Shen CJ, Pan HA, Kuo PL (corresponding author). The expression pattern of SEPT7 correlates with sperm morphology. Journal of Assisted Reproduction and Genetics 2010;27:299-307. SCI
  • Teng YN, Liao MH, Lin YB, Kuo PL, Kuo TY. The expression of LRWD1 in mouse testis and its centrosomal localization. International Journal of Andrology 2010;33:832-840. SCI
  • Hsu CC, Kuo PH, Lee IW, Su MT, Tseng JT, Kuo PL (corresponding author). Quantitative trail analysis suggests human DAZL may be involved in regulating sperm counts and motility. Reproductive BioMedicine Online 2010;11:77-83. SCI
  • Teng YN, Kuo PL, Cheng TC, Liao MH. Histone gene expression profile during spermatogenesis. Fertility and Sterility 2010;93:2447-2449. SCI
  • Su MT, Chen CH, Kuo PH, Hsu CC, Lee IW, Pan HA, Chen YT, Kuo PL (corresponding author). Polymorphisms of estrogen-related genes jointly confer susceptibility to human spermatogenic defect. Fertility and Sterility 2010;93:141-149. SCI
  • Pan HA, Lee YC, Teng YN, Tsai SJ, Kuo PL (corresponding author). CDC25 protein expression and interaction with DAZL in human corpus luteum. Fertility and Sterility 2009;92:1997-2003. SCI
  • Lien KI, Liu CJ, Kuo PL, Lee GB. Microfluid system for rapid detection of –thalassemia-1 deletion using saliva samples. Analytical Chemistry 2009; 81:4502-9. SCI
  • Lin YH, Lin YM, Wang YY, Yu YS, Lin WY, Wang YH, Wu CM, Pan HA, Chao SC, Yen H, Lin SW, Kuo PL (corresponding author). The expression level of Septin12 is critical for spermatogenesis. American Journal of Pathology 2009;174:1857-1868. SCI
  • Hsu CC, Lee IW, Su MZ, Lin YC, Hsieh C, Chen PY, Tsai HW, Kuo PL (corresponding author). Triple genetic identifies for the complete hydatidiform mole, placenta and co-existing fetus in a single in vitro-fertilized oocyte. Human Reproduction 2008;23:2686-2691. SCI
  • Huang PC, Kuo PL, Chou YY, Lin SJ, Lee CC. Association between prenatal exposure to phthalates and the health status of newborns. Environment International 2008;35:14-20. SCI
  • Lee IW, Kuan LC, Lin CH, Pan HA, Hsu CH, Tsai YC, Kuo PL, Teng YN. Association of USP26 haplotypes in Taiwanese men with severe spermatogenic defect. Asian Journal of Andrology 2008;10:896-904. SCI
  • Pan HA, Liao RW, Chung CL, Kuo PL (corresponding author) DAZL protein expression in mouse preimplantation embryo. Fertility and Sterility 2008;89:1324-1327. SCI
  • Lin1 HY, Lin SP, Tsai LP, Chao MC, Chen MR, Chuang CK, Huang CU, Tsai FJ, Chou IC, Chiu PC, Huang CH, Yen JL, Lin JL, Kuo PL. Effects of growth hormone treatment on height, weight and obesity in Taiwanese patients with Prader-Willi syndrome. Journal of Chinese Medical Association 2008;71:305–309.
  • Hsieh TY, Hsu KF, Kuo PL, Huang SC. Uterine choriocarcinoma accompanied by an extremely high human chorionic gonadotropin level and thyrotoxicosis. Journal of Obstetrics and Gynecology Research 2008;34:274-278. SCI
  • Yang SM. Chang C, Lin TI, Kuo PK. DNA hybridization measurement by self- sensing piezoresistive microcantilevers in CMOS biosensor. Sensors and Actuators 2008;B310:674-681. SCI
  • Kuo PL, Huang SC, Chang LW, Lin CH, Tsai WH, Teng YN. Association of extremely skewed X-chromosome inactivation with Taiwanese women presenting with recurrent pregnancy loss. Journal of Formosan Medical Association 2008;107:340-343. SCI
  • Chang LW, Lee IW, Kuo PL. Kuan LC. Maternal derivative chromosome 9 and recurrent pregnancy loss – a case report. Fertility and Sterility 2007;88:968. SCI
  • Huang PC, Kuo PL, Guo YL, Liao PC, Lee CC. Associations between urinary phthalate monoesters and thyroid hormones in pregnant women. Human Reproduction 2007;22:2715-2722. SCI
  • Chen RL, Wu PL, Hsu YH, Kuo PL. Evans syndrome after unrelated cord blood transplantation for disseminated Langerhans cell histiocytosis in a child. J Pediatr Hematol Oncol. 2007;29:348-50. SCI
  • Teng YN, Lin YH, Tsai YC, Hsu CC, Kuo PL, Lin YM. A simplified gene-specific screen for Y chromosome deletions in infertile men. Fertility and Sterility 2007;87:1291-1300. SCI
  • Peng HH, Kuo PL, Chao AS, Wang TH, Chang YL, Soong YK, Chang SD. Discordant semilobar holoprosencephaly in monozygotic twins with de novo inv dup(15) marker chromosome and de novo mutation on SHH gene. Fetal Diagnosis and Therapy 2007;22:389-393. SCI
  • Teng YN, Chung CL, Lin YM, Pan HA, Liao RW, Kuo PL (corresponding author). Expression of various CDC25B isoforms in human spermatozoa. Fertility and Sterility 2007;88:379-382. SCI
  • Lin HY, Lin SP, Chung CK, Chen MR, Yen YL, Lee YJ, Huang CY, Tsai LP, Niu DM, Chao MC, Kuo PL. Genotype and phenotype in patients with Prader-Willi syndrome in Taiwan. Acta Paediatrica 2007;96: 902-905. SCI
  • Lin HY, Lin SP, Yen JL, Lee YJ, Huang CY, Hung HY, Hsu CH, Kao HA, Chang JH, Chiu NC, Ho CS, Chao MC, Niu DM, Tsai LP, Kuo PL. Prader-Willi Syndrome in Taiwan. Pediatrics International 2007;49:375-379. SCI
  • Lin YW, Hsu LCL, Kuo PL. Huang WJ, Chiang HS, Yeh SD, Hsu TY, Yu YH, Hsiao KN, Cantor RM, Yen PH. Partial duplication of AZFc on the Y chromosome is a risk factor for impaired spermatogenesis in Han Chinese in Taiwan. Hum Mutation 2007;28:486-494. SCI
  • Chen TM, Kuo PL, Hsu CF, Tsai SJ, Chen MJ, Lin CW, Sun HS. Microsatellite in the 3’ untranslated region of human fibroblast growth factor 9 (FGF9) gene exhibits pleiotropic effect on modulating FGF9 protein expression. Hum Mutation 2007;28:98. SCI
  • Lee IW, Su MT, Hsu CC, Lin YH, Chen PY, Kuo PL. (corresponding author) Constitutional complex chromosomal rearrangements in azoospermic men – a case report and literature review. Urology 2006;68:1343e5-e8. SCI
  • Hsieh TY, Yu CH, Kuo PL, Chang FM. Acute viral hepatitis C-induced jaundice in pregnancy. Taiwan J Obstet Gynecol. 2006;45:180-2.
  • Chen ML, Su JM, Chen YM, Chou CY, Kuo PL. Presacral epidermoid cyst with right hydronephrosis. Taiwan J Obstet Gynecol. 2006;;45:155-8.
  • Hsieh TY, Yu CH, Kuo PL, Chang FM. Prenatal diagnosis of alobar holoprosencephaly with cystic hygroma. Taiwan J Obstet Gynecol. 2006 Jun;45(2):146-9.
  • Chen ML, Yu CH, Chang FM, Kuo PL. Paroxysmal nocturnal hemoglobinuria superimposed with preeclampsia. Taiwan J Obstet Gynecol. 2006;45:276-278.
  • Lin YH, Lin YM, Teng YN, Hsieh TYT, Lin YS, Kuo PL (corresponding author). Identification of 10 novel genes involved in human spermatogenesis by microarray analysis of testicular tissue. Fertil Steril 2006;86:1650-1658. SCI
  • Su MT, Lee IW, Kuo PL. (corresponding author). Presence of TPSY transcript and absence of transcripts of other Y-chromosomal genes in a case of microscopic gonadoblastoma. Gynecological Oncology 2006;103:357-360. SCI
  • Cheng YS, Kuo PL, Teng YN, Kuo TY, Chung CL, Lin YH, Liao RW, Lin JSN, Lin YM. Association of spermatogenic failure with decreased CDC25A expression in infertile men. Hum Reprod 2006;21:2346-2352. SCI
  • Yen-Ni Teng, Yung-Ming Lin, Hsiao-Fang Sunny Sun, Pei-Yang Hsu, Chia-Ling Chung, Pao-Lin Kuo. (corresponding author) Association of DAZL haplotypes with spermatogenic failure in infertile men. Fertil Steril 2006;86:129-135. SCI
  • Chao-Chin Hsu, Pao-Lin Kuo, Louise Chuang, Ying-Hung Lin, Yen-Ni Teng, Yung-Ming Lin. Uniform Deletion Junctions of Complete AZFc Deletion in Taiwanese Infertile Men. Asian Journal of Andrology 2006;8:205-211. SCI
  • Chen YF, Kuo PL, Tsai SJ, Chen KF, Chan HH, Chen CM, Sun HF. Computational analysis and refinement of sequence structure on chromosome 22q11.2 region: application to the development of quantitative real-time PCR assay for clinical diagnosis. Genomics 2006;87:290-297. SCI
  • Lin YM, Teng YN, Chung CL, Tsai WC, Lin YH, Lin JSN, Kuo PL. (corresponding author) Decreased mRNA transcripts of M-phase promoting factor and its regulators in the testes of infertile men. Hum Reprod 2006;21:138-144. SCI
  • Pan HA, Lin YS, Huang JR, Lee KH, Lin YH, Kuo PL. (corresponding author) Expression patterns of the DAZ associated protein ﹣DAZAP1﹣ in rat and human ovaries. Fertil Steril 2005;84(Suppl 2):1089-1094. SCI
  • Tsai PY, Lin YH, Chang CH, Chang FM, Kuo PL. Ring chromosome 7 presenting with intrauterine growth restriction and multiple anomalies. Taiwanese J Obstet Gynecol 2005;44:297-299.
  • Su MT, Hsu KF, Kuo PL. (corresponding author) Delayed uterine rupture after fetal reduction in a case of cornual heterotopic prgnancy. Taiwanese J Obstet Gynecol 2005;44:270-272.
  • Lin YW, Thi DAH, Kuo PL, Hsu CC, Huang BD, Yu YH, Vogt PH, Krause W, Ferlin A, Foresta C, Bienvunu T, Schempp W, Yen PH. Polymorphisms associated with DAZ genes on the human Y chromosome. Genomics 2005;86:431-438. SCI
  • Su PH, Kuo PL, Chen SJ, HuangSC, Chen JP, Hung HM. Six cases of deletion 9p24 and trisomy 19q13.4 inherited from a familial balanced translocation. J Formos Med Assoc. 2005; 104:525-30. SCI
  • Chou YY, ChaoSC, Kuo PL, Lin SJ. A 38.8 kb deletion mutation of the iduronate-2-sulfatase gene in a patient with Hunter syndrome. J Formos Med Assoc 2005;104:273-275.SCI
  • Yeh SH, Lin CJ, Kuo PL, Chang KC, Hwang YH. Genotyping of SYT-SSX in case of phalangel synovial sarcoma. Changhua J Med 1005;10:108-112.
  • Wakui K, Gregato G, Ballif BC, Glotzbach CD, Bailey KA, Kuo PL, Sue WC, Sheffield L, Irons M, Gomez EG, Hecht JT, Potocki L, Shaffer L. Construction of a natural panel of 11p11.2 deletions and further delineation of the critical region involved in Potocki-Shaffer syndrome. Eur J Hum Genet 2005;13:528-540.SCI
  • Lin YH, Chuang L, Lin YM, Lin YH, Teng YN, Kuo PL. (corresponding author) Isochromosome of Yp in a man with Sertoli cell only syndrome. Fertil Steril 2005;83:764-766. SCI
  • Kang L, Kuo PL, Lee KH, Liu YC, Chang CH, Chang FM, Lin SJ. (corresponding author) Late onset growth restriction in Galloway-Mowat syndrome－ a case report. Prenat Diagn 2005;25:159-162. SCI
  • Lin YM, Kuo PL, Lin YH, Teng YN, Lin JSN. Messenger RNA transcripts of the meiotic regulator BOULE in the testis of azoospermic men and their application in predicting the successful sperm retrieval. Hum Reprod 2005;20:782-788. SCI
  • Chuang L, Wakui K, Sue WC, Su MH, Shaffer LG, Kuo PL. (corresponding author) Interstitial deletion 11(p11.12p11.2) and analphoid marker formation results in inherited Potocki-Shaffer syndrome. Am J Med Genet A 2005;133:180-183. SCI
  • Wang YM, Chuang L, Wang BT, Kuo PL. (corresponding author) Maternal uniparental disomy 15 in a patient of Prader-Willi syndrome with an additional small inv dup(15) chromosome. J Formos Med Assoc 2004;103;943-947. SCI
  • Kuo PL, Guo HR. Mechanism of recurrent spontaneous abortions in women with mosaicism of X-chromosome aneuploidies. Fertil Steril 2004;82:1594-1601. SCI
  • Chou YY, Chen CC, Kuo PL, Tsai WH, Lin SJ. Russel-Silver syndrome: molecular diagnosis of maternal uniparental disomy of chromosome 7 using methylation-specific polymerase chain reaction assay and single nucleotide polymorphisms genotyping. J Formos Med Assoc 2004; 103:797-802. SCI
  • Chen CJ, Hsu ML, Yuh YS, Cheng SN, Kuo PL, Lee CM. Early diagnosis of Prader-Willi syndrome in a newborn. Acta Paediatr Tw 2004;45:108-110.
  • Hwu WL, Kuo PL, HuangYT, Chen YH, Chu SY. Partial trisomy 1 with congenital hydrocephalus and hypogammaglobinemia: report of one case. Acta Paediatr Tw 2004; 45:97-99.
  • Lin YH, Lin YM, Lin YH, Chuang L, Wu SY, Kuo PL. (corresponding author) Ring (Y) in two azoospermic men. Am J Med Genet 2004;128A:209-213. SCI
  • Shiue CN, Lin YH, Kuam LC, Lii LM, Tsai WH, Chen YJ, Lin SJ, Kuo PL. Cytogenetic surveillance of mentally-retarded school children in Southern Taiwan. J Formos Med Assoc 2004;103:218-224. SCI
  • Kuo PL, Wang ST, Lin YM, Lin YH, Teng YN, Hsu CC. Expression profiles of DAZ gene family in human testis with and without spermatogenic failure. Fertil Steril 2004;81:1034-1040. SCI
  • Lin YM, Huang WJ, Lin JSN, Kuo PL. (corresponding author) Progressive depletion of germ cells in a man with nonmosaic Klinefelter’s syndrome: optimal time for sperm recovery. Urology 2004;63:380-381. SCI
  • Kuo PL, Lin YH, Teng YN, Hsu CC, Lin JSN, Lin YM. Transcriptional levels of four Y chromosome-linked AZF genes in azoospermic men and their association with successful sperm retrieval. Urology 2004;63:131-136. SCI
  • Shiue CN, Chou YY, Chuang L, Tsai WH, Tsai SC, Wu JM, Kuo PL, Lin SJ. Analysis of clinical features of Williams-Beuren syndrome referred for molecular cytogenetic study. Tzu-Chi Med J 2004;16:17-23.
  • Chen WH, Sue WC, Kuo PL, Su MH, Lin CL. Potocki-Shaffer syndrome: report of one case. Acta Paediatr Tw 2003;44:242-260.
  • Su PH, Kuo PL, Chen SJ, Hung HM, Yi TH, Chen JY. De novo 4p- syndrome with oligohydramnios sequence. J Formos Med Assoc 2003;102:647-649. SCI
  • Lin TY, Huang CC, Chiang CH, Kuo PL, Lin SJ. Nonverbal communication skills in children with Prader-Willi syndrome (PWS). Tzu Chi Med J 2003;15:311-320.
  • Kuo PL, Lin CC, Lin YH, Guo HR. Placental sonolucency and pregnancy outcome in women with elevated second trimester serum alpha-fetoprotein levels. J Formos Med Assoc 2003;102:319-325. SCI
  • Shih MC, Peng CT, Chang JY, Liu SC, Kuo PL, Chang JG. Hb Prato [alpha31(B12)Arg à Ser (A2)] and alpha-thalassemia in a Taiwanese. Hemoglobin 2003;27:45-47. SCI
  • Peng CT, LiuSC, Chiou SS, Kuo PL, Shih MC, Chang JY, Chang JG. Molecular characterization of deletional forms of b–thalassemia in Taiwan. Ann Hematol 2003;82:33-36. SCI
  • Chuang L, Kuo PL, Yang HB, Chien CH, Chen PY, Chang CH, Chang FM. (corresponding author) Prenatal diagnosis of holoprosencephaly in two fetuses with der (7)t(1;7)(q32;q32)pat inherited from the father with double translocations. Prenat Diagn 2003;23:134-137. SCI
  • Chien YH, Yang YH, Chu SY, Hwu WL, Kuo PL, Chiang BL. DiGeorge sequence with hypogammaglobulinemia: a case report. J Microbio Immunol Infect 2002;35:187-190. SCI
  • Liu YC, Chang CH, Yu CH, Kuo PL, Chang FM. Prenatal diagnosis of placental, umbilical cord, and amniotic fluid abnormalities in a medical center of Southern Taiwan. Taiwanese J Obstet Gynecol 2002;42:35-41.
  • Chien YH, Kuo PL, Hwu WL. An infant with heart murmur and dysmorphic face. Acta Paediatr Tw 2002;43:241-243.
  • Tsai WH, Lin SJ, Chen CT, Shiue CN, Tsai SC, Wu CJ, Kuo PL. (corresponding author) Diagnosis of Prader-Willi syndrome in the neonatal period. Clinical Neonatology 2002;9:24-27.
  • Kang L, Kuo PL, Guo HR. (corresponding author) Reproducibility of magnetic-activated cell sorting for fetal cell isolation. Taiwanese J Obstet Gynecol 2002;41:163-171.
  • TengYN, Lin YM, Lin YH, Tsao SY, Hsu CC, Lin SJ, Kuo PL. (corresponding author) Association of a single nucleotide polymorphism of the deleted-in- azoospermia-like (DAZL) gene with susceptibility to spermatogenic failure. J Clin Endocrinol & Metab 2002;87:5258-5264. SCI
  • Teng YN, Tsai WH, Wu CJ, Lin SJ, Chen YJ, Kuo PL. (corresponding author) Referral diagnosis of Prader-Willi syndrome and Angelman syndrome based on methylation-specific polymerase chain reaction. J Formos Med Assoc2002;101:488-494. SCI
  • Pan HA, Tsai SJ, Chen CW, Lee YC, Lin YM, Kuo PL. (corresponding author) Expression of DAZL protein in human corpus luteum. Mol Hum Reprod 2002;8:540-545. SCI
  • Kuo PL. Maternal trisomy 21 mosaicism and recurrent spontaneous abortion. Fertil Steril 2002;78:432-433. SCI
  • Chang KC, Chen PI, Huang ZH, Lin YM, Kuo PL. (corresponding author) Adrenal myelolipoma with translocation (3;21)(q25;p11). Cancer Genet Cytogenet 2002;134:77-80. SCI
  • Lin YM, Lin YH, Teng YN, Hsu CC, Lin JSN, Kuo PL. (corresponding author) Gene-based screening for Y chromosome deletions in Taiwanese men presenting with spermatogenic failure. Fertil Steril 2002;77:897-903.SCI
  • Pan HA, Kuo PL. (corresponding author) Transvaginal color flow Doppler ultrasonography for detecting acquired arteriovenous malformation of the uterus. Taiwanese J Obstet Gynecol 2002;41:25-29.
  • Lin YM, Chen CW, Sun HS, Tsai SJ, Lin J SN, Kuo PL. (corresponding author) Presence of DAZL transcript and protein in human spermatozoa. Fertil Steril 2002;77:626-629. SCI
  • Lin YM, Chen CW, Sun HS, Tsai SJ, Hsu CC, Teng YN, Lin J SN, Kuo PL. (corresponding author) Expression patterns and transcript concentrations of the autosomal DAZL gene in testes of azoospermic men. Mol Hum Reprod 2001;7:1015-1022. SCI
  • Lin YM, Teng YN, Lee PC, Lin YH, Hsu CC, Lin J SN, Kuo PL. (corresponding author) AZFa candidate gene deletions in Taiwanese patients with spermatogenenic failure. J Formos Med Assoc 2001;100:592-597. SCI
  • Chang LW, Chen PY, Kuo PL, (corresponding author) Chang FM. Prenatal diagnosis of a fetus with megacystis and monosomy 21. Prenat Diagn 2001;21:512-513. SCI
  • Hsu HP, Kuo PL, Wu MH, Wu TJ, Dai YC, Tzeng CC, Lin SJ. (corresponding author) Microscopic gonadobalstoma in a patient with 46,XY gonadal dysgenesis. Taiwanese J Obstet Gynecol 2001;40:77-82.
  • Lin YH, Kuo PL, Chang FM. (corresponding author) Fetal sedation by maternal intravascular Midazolam injection. Taiwanese J Obstet Gynecol 2001;40:21-24.
  • Tzeng CH, Lin SJ, Chen YJ, Kuo PL, Jong YJ, Tsai LP, Chen RM. An effective strategy of using molecular testing to screen mentally retarded individuals for fragile X syndrome. Diagn Mol Pathol 2001;10:34-40. SCI
  • Kuo PL, Guo HR. Magnetic-activated cell sorting significantly decreases hybridization efficiency of fluorescence in situ hybridization. Prenat Diagn

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