Name: Ping Lin
Lab place: 82-1137 room, Department of Microbiology and Immunology 
E-mail: lingpin@mail.ncku.edu.tw
   
   
 

Education

  • Post-doctoral fellow, University of Texas, MD Anderson Cancer Center
  • Ph.D., Baylor College of Medicine (U.S.A.)
 

Research

  • Identification and characterization of novel innate immune regulators.
  • Interactions between viruses and the host innate immune system.

 

Publication

  • Wei-Shan Hung, Pin Ling, Ju-Chien Cheng, Shy-Shin Chang & Ching-Ping Tseng . 2016. Disabled-2 is a negative immune regulator of lipopolysaccharide-stimulated Toll-like receptor 4 internalization and signaling. Scientific Reports 6: 35343
  • Yao HW, Ling P, Tung YY, Hsu SM, Chen SH. 2014. In Vivo Reactivation of Latent Herpes Simplex Virus 1 in Mice Can Occur in the Brain before Occurring in the Trigeminal Ganglion. Journal of virology 88:11264-11270.
  • Wan SW, Lin CF, Yeh TM, Liu CC, Liu HS, Wang S, Ling P, Anderson R, Lei HY, Lin YS. 2013. Autoimmunity in dengue pathogenesis. Journal of the Formosan Medical Association 112: 3-11
  • Yao HW, Ling P, Chen SH, Tung YY. 2012. Factors affecting herpes simplex virus reactivation from the explanted mouse brain. Virology 433: 116-23
  • Wang LC, Kao CM, Ling P, Su IJ, Chang TM, Chen SH. 2012. CD4 T-cell-independent antibody response reduces enterovirus 71 lethality in mice by decreasing tissue viral loads. Clinical and Developmental Immunology 2012: 580696
  • Chen KR, Chang CH, Huang CY, Lin CY, Lin WY, Lo YC, Yang CY, Hsing EW, Chen LF, Shih SR, Shiau AL, Lei HY, Tan TH, Ling P. 2012. TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity. The Journal of Biological Chemistry 287: 32216-21
  • Lin LH, Ling P, Liu MF. 2011. The potential role of interferon-regulatory factor 7 among Taiwanese patients with systemic lupus erythematosus. The Journal of Rheumatology 38: 1914-9
  • Chang CH, Lai LC, Cheng HC, Chen KR, Syue YZ, Lu HC, Lin WY, Chen SH, Huang HS, Shiau AL, Lei HY, Qin J, Ling P. 2011. TBK1-associated protein in endolysosomes (TAPE) is an innate immune regulator modulating the TLR3 and TLR4 signaling pathways. The Journal of Biological Chemistry 286: 7043-51
  • Huang WY, Su YH, Yao HW, Ling P, Tung YY, Chen SH, Wang X. 2010. Beta interferon plus gamma interferon efficiently reduces acyclovir-resistant herpes simplex virus infection in mice in a T-cell-independent manner. Journal of General Virology 91: 591-8
  • Ling P, Lu TJ, Yuan CJ, Lai MD. 2008. Biosignaling of mammalian Ste20-related kinases. Cell Signal 20: 1237-47
  • Li ZH, Li CM, Ling P, Shen FH, Chen SH, Liu CC, Yu CK. 2008. Ribavirin reduces mortality in enterovirus 71-infected mice by decreasing viral replication. The Journal of Infectious Diseases 197: 854-7
  • Lee JC, Won SJ, Chao CL, Wu FL, Liu HS, Ling P, Lin CN, Su CL. 2008. Morusin induces apoptosis and suppresses NF-kappaB activity in human colorectal cancer HT-29 cells. Biochemical and Biophysical Research Communications 372: 236-42
  • Giri DK, Ali-Seyed M, Li LY, Lee DF, Ling P, Bartholomeusz G, Wang SC, Hung MC. 2005. Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor. Molecular and Cellular Biology 25: 11005-18
  • Ma W, Xia C, Ling P, Qiu M, Luo Y, Tan TH, Liu M. 2001. Leukocyte-specific adaptor protein Grap2 interacts with hematopoietic progenitor kinase 1 (HPK1) to activate JNK signaling pathway in T lymphocytes. Oncogene 20: 1703-14
  • Ling P, Meyer CF, Redmond LP, Shui JW, Davis B, Rich RR, Hu MC, Wange RL, Tan TH. 2001. Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling. The Journal of Biological Chemistry 276: 18908-14
  • Ito Y, Pandey P, Sathyanarayana P, Ling P, Rana A, Weichselbaum R, Tan TH, Kufe D, Kharbanda S. 2001. Interaction of hematopoietic progenitor kinase 1 and c-Abl tyrosine kinase in response to genotoxic stress. The Journal of Biological Chemistry 276: 18130-8
  • McAveney KM, Book ML, Ling P, Chebath J, Yu-Lee L. 2000. Association of 2',5'-oligoadenylate synthetase with the prolactin (PRL) receptor: alteration in PRL-inducible stat1 (signal transducer and activator of transcription 1) signaling to the IRF-1 (interferon-regulatory factor 1) promoter. Molecular Endocrinology 14: 295-306
  • Ling P, Yao Z, Meyer CF, Wang XS, Oehrl W, Feller SM, Tan TH. 1999. Interaction of hematopoietic progenitor kinase 1 with adapter proteins Crk and CrkL leads to synergistic activation of c-Jun N-terminal kinase. Molecular and Cellular Biology 19: 1359-68
  • Chang KS, Lin CI, Ling P, Lin KH, Lin HC, Twu SJ. 1994. Molecular subtypes of env sequences around V3 region of human immunodeficiency virus type 1 in Taiwan. European Journal of Epidemiology 10: 247-50