Education

• 1991.9 ~ 1997.8 Ph.D. Columbia University, New York City
• 1983.9 ~ 1990.6 M.D. National Taiwan University

Research

• An integrated bioinformatic and biomedical approach for cancer research.
• New tumor markers for molecular pathology.

Training And Appointments

• 2006.3~ Division head, Division of Molecular Pathology, Department of Pathology, National Cheng Kung University Hospital
• 2005.8~ Associate professor, Department of Pathology, NCKU
• 2003.10~2004.3 Research fellow, Division of Gynecologic Pathology, Department of Pathology, Johns Hopkins Medical Center
• 2001.8~ Attending physician, Department of Pathology, NCKU Hospital
• 1997.9~2001.7 Resident, Department of Pathology, NCKU Hospital

Research

• Hsu CC, Chiang CW, Cheng HC, Chang WT, Chou CY, Tsai HW, Lee CT, Wu ZH, Lee TY, Chao A, Chow NH, *Ho CL (corresponding). Identifying LRRC16B as an oncofetal gene with transforming enhancing capability using a combined bioinformatics and experimental approach. Oncogene. 2011 Feb 10;30(6):654-67.
• Yeh YM, Chen YL, Cheng HY, Su WC, Chow NH, *Chen TY, *Ho CL (co-corresponding). High percentage of JAK2 exon 12 mutation in Asian patients with polycythemia vera. Am J Clin Pathol. 2010 Aug; 134(2) 266-70.
• Chen YL, Su IJ, Cheng HY, Chang KC, Lu CC, Chow NH, *Ho CL (co-corresponding), *Huang W. BIOMED-2 protocols to detect clonal immunoglobulin and T cell receptor gene rearrangements in B- and T-cell lymphomas in Southern Taiwan. Leuk Lymphoma. 2010 Apr;51(4):650-5.
• Yen KH, *Ho CL (corresponding), Lee C. The analysis of inconsistencies between cytogenetic annotations and sequence mapping by defining the imprecision zones of cytogenetic banding. Bioinformatics. 2009 Apr 1;25(7):845-52.
• Tsai HW, Chow NH, Lin CP, Chan SH, Chou CY, *Ho CL (corresponding). The significance of prohibitin and c-Met/HGFR expressions in the progression of cervical adenocarcinoma. Human Pathology. 2006 Feb; 37(2):198-204.
• Yen KH, Lee C, Liu HS, *Ho CL (corresponding). A precise and scalable method for querying genes in chromosomal banding regions based on cytogenetic annotations. Bioinformatics. 2005 Sep; 1(17):3469-74.
• Pohl G, Ho CL (equal contribution), Kurman RJ, Bristow R, Wang TL, *Shih IeM. Inactivation of the mitogen-activated protein kinase pathway as a potential target-based therapy in ovarian serous tumors with KRAS or BRAF mutations. Cancer Research. 2005 Mar; 65(5):1994-2000.
• Ho CL, Kurman RJ, Dehari R, Wang TL, *Shih IeM. Mutations of BRAF and KRAS precede the development of ovarian serous borderline tumors. Cancer Research. 2004 Oct; 64(19):6915-8.
• Wang L, C.-L. Ho, D. Sun, R.K. Liem, A. Brown. Rapid movement of axonal neurofilaments interrupted by prolonged pauses. Nature Cell Biology. 2000. Mar; 2(3):137-41.