Name: Kung-Chao Chang
Lab place: Department of Pathology, National Cheng Kung University, College of Medicine, Tainan, TAIWAN. 
E-mail: changkc@mail.ncku.edu.tw 


 

Education

2001-09 Ph.D. Institute of Clinical Medicine, Medical College, National Cheng Kung University, Tainan, TAIWAN.
2002-03 Research Fellow Department of Hematopathology, M.D. Anderson Cancer 
Center, Houston, Texas, U.S.A.
1986-93 MD China Medical College, Taichung, TAIWAN.
 

Research

  • The role of EBV in Hodgkin lymphoma
  • The role of malignant effusions in diffuse large B-cell lymphoma

 

Representative Publications

  1. Chang KC*(corresponding author), Lee JC, Wang YC, Hung LY, Huang Y, Huang WT, Wang RC, Chen TC, Tsai YS, and Medeiros L. Jeffrey. Polyclonality in Sclerosing Angiomatoid Nodular Transformation of the Spleen. Am J Surg Pathol. 2016 In press

  2. Dai YH, Hung LY, Chen RY, Lai CH, Chang KC*(corresponding author).ON 01910.Na inhibits growth of diffuse large B-cell lymphoma by cytoplasmic sequestration of sumoylated C-MYB/TRAF6 complex. Transl Res. 2016 Apr 13. pii: S1931-5244(16)30019-6. doi: 0.1016/j.trsl.2016.04.001. [Epub ahead of print]

  3. Chang C, Wu SY, Kang YW, Lin KP, Chen TY, Medeiros LJ, Chang KC*(corresponding author). High Levels of Regulatory T Cells in Blood Are a Poor Prognostic Factor in Patients With Diffuse Large B-Cell Lymphoma. Am J Clin Pathol. 2015 Dec;144(6):935-44

  4. Chen YP, Huang HY, Lin KP, Medeiros LJ, Chen TY, Chang KC*(corresponding author). Malignant effusions correlate with poorer prognosis in patients with diffuse large B-cell lymphoma. Am J Clin Pathol. 2015 May;143(5):707-15.

  5. Chang C, Lin CH, Cheng AL, Medeiros JL, Chang KC*(corresponding author).Primary Central Nervous System Diffuse Large B-cell Lymphoma Has Poorer Immune Cell Infiltration and Prognosis than Peripheral Counterpart. Histopathology. 2015 Nov;67(5):625-35. Mar 31. doi: 10.1111/his.12706. [Epub ahead of print]

  6. Chang KC*(co-corresponding author), Wang YC, Hung LY, Huang WT, Tsou JH, M Jones D, Song HL, Yeh YM, Kao LY, Medeiros LJ*. Monoclonality and cytogenetic abnormalities in hyaline vascular Castleman disease. Mod Pathol. 2014 Jun;27(6):823-31. 成醫研計畫編號 NCKUH-10002020 & 國科會NSC 100-2320-B-006-005-MY3 & 衛生署 DOH101-TD-C-111-003

  7. Chen YP, Jones D, Chen TY, Chang KC* (corresponding author). Epstein-Barr virus present in T cells or B cells shows differential effects on hemophagocytic symptoms associated with outcome in T-cell lymphomas. Leuk Lymphoma. 2014 Sep;55(9):2038-47. 成醫研計畫編號 NCKUH-10004005 & 國科會NSC 100-2320-B-006-005-MY3 & 衛生署 DOH101-TD-C-111-003.

  8. Chang KC*(co-corresponding author), Chang WC, Chang Y, Hung LY, Lai CH, Yeh YM, Chou YW, Chen CH*. Ran GTPase-Activating Protein 1 Is a Therapeutic Target in Diffuse Large B-Cell Lymphoma. PLoS One. 2013 Nov 6;8(11):e79863. 成醫研計畫編號 NCKUH-10204008 & 國科會NSC 100-2320-B-006-005-MY3 & 衛生署 DOH101-TD-C-111-003.

  9. Chang KC*(corresponding author), Lu YC, Lin MJ, Chen HY, Jin YT.Desmoplastic Tumor-associated Stroma versus Neural Tissue in Central Nervous System Metastasis: Effects of different microenvironments on tumor growth. Histopathology. 2011 Jul;59(1):31-9. SCI 成醫研計畫編號 NCKUH-99-04001

  10. Chang KC, Chen PC, Chen YP, Chang Y, Su IJ*.Dominant expression of survival signals of endoplasmic reticulum stress response in Hodgkin lymphoma. Cancer Sci. 2011 Jan;102(1):275-81. [Epub 2010 Nov 10.] SCI 成醫研計畫編號 NCKUH-97-02008 & 國科會NSC 97-2320-B-006-022-MY3